Pregled bibliografske jedinice broj: 1271209
A complex interplay between autonomic symptoms and symptoms of depression, anxiety, and stress
A complex interplay between autonomic symptoms and symptoms of depression, anxiety, and stress // Neurological Sciences, Online ahead of print (2023), 37016063, 10 doi:10.1007/s10072-023-06787-9 (međunarodna recenzija, članak, znanstveni)
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Naslov
A complex interplay between autonomic symptoms and
symptoms of depression, anxiety, and stress
Autori
Junaković, Anamari ; Skočić Hanžek, Milena ; Adamec, Ivan ; Krbot Skorić, Magdalena ; Habek, Mario
Izvornik
Neurological Sciences (1590-1874) Online ahead of print
(2023);
37016063, 10
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Anxiety ; Autonomic symptoms ; COMPASS-31 ; Depression ; Stress
Sažetak
Background: We evaluated the influence of symptoms of depression, anxiety, and stress on the results of COMPASS-31 in a large population of people referred to the head-up tilt test (HUTT) and healthy controls (HC). Methods: Nine hundred fifty-nine consecutive patients referred to HUTT and 518 HC were enrolled. All participants completed Composite Autonomic Symptom Score-31 (COMPASS-31). Stress symptoms were evaluated by Depression, Anxiety, and Stress-21 (DASS-21) questionnaire. We corrected the result of the COMPASS-31 with the independent predictors in order to improve the specificity of the test. Results: In both patients and HC, COMPASS-31 was higher in participants with depression, anxiety, and stress symptoms (all p < 0.001). In a multivariable linear regression analysis, HC was negative, while female sex and symptoms of depression, anxiety, and stress were independent positive predictors of COMPASS-31. In HC, COMPASS- 31 had a median of 7.913, and this value differentiated between HC and patients with a high sensitivity of 87% and low specificity of 50%. In order to adjust the value of COMPASS-31 with the parameters that were significant in the multivariable linear regression model, we calculated the new corrected COMAPSS-31 (cCOMPASS- 31), which had comparable sensitivity of 77%, but an increased specificity of 73%. Conclusion: This study has shown that symptoms of depression, anxiety, and/or stress worsen the perceived severity of autonomic symptoms in people with symptoms of orthostatic intolerance and healthy population. cCOMPASS-31 is a valuable tool that can help clinicians in discerning the true autonomic background of patients' complaints.
Izvorni jezik
Engleski
Znanstvena područja
Elektrotehnika, Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Fakultet elektrotehnike i računarstva, Zagreb,
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb
Profili:
Mario Habek (autor)
Ivan Adamec (autor)
Anamari Junaković (autor)
MAGDALENA KRBOT SKORIĆ (autor)
Milena Skočić Hanžek (autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE