Naslov
IgG N-glycosylation is not influenced by severity of complications in type 1 diabetes

Autori
Plavša, Branimir ; Kološnjaj, Ivona ; Bulum, Tomislav ; Tomić, Martina: Vučković Rebrina, Sandra ; Vučić Lovrenčić, Marijana ; Duvnjak, Lea ; Gornik, Olga

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
HDBMB 2022 Congress – From Science to Knowledge

Mjesto i datum
Brela, Hrvatska, 28.09.2022. - 01.10.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
glycosylation, N-glycosylation, IgG, diabetes, type 1

Sažetak
N-glycosylation of immunoglobulin G (IgG) is known to influence the antibody function. Changes in IgG N-glycome associate with many inflammatory conditions and were reported in early stages of type 1 and type 2 diabetes mellitus (DM). IgG N- glycosylation was also studied in relation to disease progression in type 2 DM and was found to associate with diabetes complications. Although type 1 and type 2 DM share complications, these findings may not apply to type 1 DM due to different pathophysiology involved and a longer disease duration prior to complication manifestation.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

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