Naslov
Triazole derivatives as potential eco-friendly pesticides – an in vitro and in vivo study

Autori
Šubarić, Domagoj ; Karnaš, Maja ; Majić, Ivana ; Rastija, Vesna

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
28. HSKIKI BOOK OF ABSTRACTS / Rogošić, Marko - Zagreb : Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2023, 132-132

Skup
28th Croatian Meeting of Chemists and Chemical Engineers

Mjesto i datum
Rovinj, Hrvatska, 28.03.2023. - 31.03.2023

Vrsta sudjelovanja
Poster

Vrsta recenzije
Recenziran

Ključne riječi
triazoles ; eco-friendly pesticides ; acetylcholinesterase ; nematicidal activity

Sažetak
The substantial increase in pest’s resistance to commonly used pesticides as well as the concern of growing environmental pollution have been the biggest challenges agricultural industry had to face in recent years. Large efforts have been made to produce a variety of novel and environmentally sustainable compounds to be used as an alternative to commercially available pesticides. [1] A set of 36 newly synthesized triazole derivatives have been assayed as potential acetylcholinesterase inhibitors by utilizing the Ellman’s protocol. [2] The highest inhibition percentages were obtained with compounds 7h (68.32%), KM35 (49.77%), KM16 (48.04%), KM18 (47.82%), and KM19 (39.89%). In vivo study was performed on two species of nematodes ; Heterorhabditis bacteriophora and Steinernema feltiae. The nematodes were exposed to aforementioned compounds in the period of 72 h. The highest mortality rate of Heterorhabditis bacteriophora species was observed with the compound KM16 with the value of 75.0% after 48 h of incubation, while he highest mortality rate of Steinernema feltiae was observed with the compound KM18 with the value of 50.0% after 48 and 72 h of incubation. The inhibition percentages do not seem to correlate with the in vivo results, as the compound 7h had one of the lowest mortality rates within the tested group of compounds among the both nematode species.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Poljoprivreda (agronomija)

POVEZANOST RADA