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Pregled bibliografske jedinice broj: 1267934

A Clinical Microbiologist's Guide to Diagnosing Prosthetic Joint Infections (PJIs)


Janeš, Andrea; Vučković, Darinka; Abram, Maja; Mađarević, Tomislav; Jeličić, Joško
A Clinical Microbiologist's Guide to Diagnosing Prosthetic Joint Infections (PJIs) // CROCMID 2022, Abstract Book / Santini, Marija ; Vraneš, Jasmina (ur.).
Šibenik, 2022. PO-19, 1 (poster, domaća recenzija, sažetak, stručni)


CROSBI ID: 1267934 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
A Clinical Microbiologist's Guide to Diagnosing Prosthetic Joint Infections (PJIs)

Autori
Janeš, Andrea ; Vučković, Darinka ; Abram, Maja ; Mađarević, Tomislav ; Jeličić, Joško

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
CROCMID 2022, Abstract Book / Santini, Marija ; Vraneš, Jasmina - Šibenik, 2022

Skup
13th CROATIAN CONGRESS OF CLINICAL MICROBIOLOGY 10th CROATIAN CONGRESS ON INFECTIOUS DISEASES with international participation

Mjesto i datum
Šibenik, Hrvatska, 20.10.2022. - 23.10.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Prosthetic Joint Infection, Diagnosis, Clinical Microbiologist

Sažetak
Aim: In developed countries, prosthetic joint infections (PJI) emerged as the most complex orthopedic infections to diagnose and treat. Although sonication of explanted prostheses significantly improved microbiological diagnostics of PJI, using conventional cultures is still laborious and time-intensive. Therefore, we aim to present the current developments in new diagnostic methods of PJI and how they compare with conventional cultures of synovial fluid, periprosthetic tissue samples, and sonication fluid. Particular emphasis is going to be placed on molecular techniques such as multiplex polymerase chain reaction (PCR), 16S rDNA sequencing, metagenomic sequencing, matrix-assisted laser desorption/ionization time-of-flight (MALDI- TOF), and technology that combines MALDI-TOF and PCR, as they are utilized to detect pathogens most likely responsible for the development of PJI. Of other nonculture-based methods, we shall briefly cover fluorescent in situ hybridization (FISH), microarrays, and microcalorimetry. Methods: A literature search was conducted in the Web of Science (WoS) database using relevant keywords: („prosthetic joint infection“ OR „pji“) AND „molecular diagnostic*“. Results: The search returned 27 results, of which seven were excluded due to the subject being unrelated to the object of this review. The rest of the articles were thoroughly read and used to write the review. Conclusion: Although molecular diagnostic methods such as multiplex PCR and genomic and metagenomic sequencing seem very promising for diagnosing PJI, implementing them in PJI microbiological protocols will not single-handedly solve all the challenges clinicians and clinical microbiologists currently face. These methods are presently used only to complement the results of conventional cultures and should be interpreted in the context of other laboratory, pathology, and clinical findings. In the foreseeable future, the diagnosis of PJI and the decision on the best course of action in specific clinical cases will remain a joint effort of multidisciplinary teams.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
--uniri-biomed-18-277 - Bakterijska patogeneza - od istraživanja do kliničke primjene (Abram, Maja) ( CroRIS)

Ustanove:
Medicinski fakultet, Rijeka,
Klinička bolnica "Sveti Duh",
Klinika za ortopediju Lovran,
Klinički bolnički centar Rijeka


Citiraj ovu publikaciju:

Janeš, Andrea; Vučković, Darinka; Abram, Maja; Mađarević, Tomislav; Jeličić, Joško
A Clinical Microbiologist's Guide to Diagnosing Prosthetic Joint Infections (PJIs) // CROCMID 2022, Abstract Book / Santini, Marija ; Vraneš, Jasmina (ur.).
Šibenik, 2022. PO-19, 1 (poster, domaća recenzija, sažetak, stručni)
Janeš, A., Vučković, D., Abram, M., Mađarević, T. & Jeličić, J. (2022) A Clinical Microbiologist's Guide to Diagnosing Prosthetic Joint Infections (PJIs). U: Santini, M. & Vraneš, J. (ur.)CROCMID 2022, Abstract Book.
@article{article, author = {Jane\v{s}, Andrea and Vu\v{c}kovi\'{c}, Darinka and Abram, Maja and Ma\djarevi\'{c}, Tomislav and Jeli\v{c}i\'{c}, Jo\v{s}ko}, year = {2022}, pages = {1}, chapter = {PO-19}, keywords = {Prosthetic Joint Infection, Diagnosis, Clinical Microbiologist}, title = {A Clinical Microbiologist's Guide to Diagnosing Prosthetic Joint Infections (PJIs)}, keyword = {Prosthetic Joint Infection, Diagnosis, Clinical Microbiologist}, publisherplace = {\v{S}ibenik, Hrvatska}, chapternumber = {PO-19} }
@article{article, author = {Jane\v{s}, Andrea and Vu\v{c}kovi\'{c}, Darinka and Abram, Maja and Ma\djarevi\'{c}, Tomislav and Jeli\v{c}i\'{c}, Jo\v{s}ko}, year = {2022}, pages = {1}, chapter = {PO-19}, keywords = {Prosthetic Joint Infection, Diagnosis, Clinical Microbiologist}, title = {A Clinical Microbiologist's Guide to Diagnosing Prosthetic Joint Infections (PJIs)}, keyword = {Prosthetic Joint Infection, Diagnosis, Clinical Microbiologist}, publisherplace = {\v{S}ibenik, Hrvatska}, chapternumber = {PO-19} }




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