Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1264961

Equilibrium and kinetic studies on the reactions of aquapentacyanoferrate(II) with 4-imidazoline-2- thiones


Damjanović, Vladimir; Musija, Danijela; Picek, Igor; Foretić, Blaženka
Equilibrium and kinetic studies on the reactions of aquapentacyanoferrate(II) with 4-imidazoline-2- thiones // 28th Croatian Meeting of Chemists and Chemical Engineers: Book of Abstracts / Rogošić, Marko (ur.).
Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2023. str. 68-68 (poster, domaća recenzija, sažetak, znanstveni)


CROSBI ID: 1264961 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Equilibrium and kinetic studies on the reactions of aquapentacyanoferrate(II) with 4-imidazoline-2- thiones

Autori
Damjanović, Vladimir ; Musija, Danijela ; Picek, Igor ; Foretić, Blaženka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
28th Croatian Meeting of Chemists and Chemical Engineers: Book of Abstracts / Rogošić, Marko - Zagreb : Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2023, 68-68

Skup
28th Croatian Meeting of Chemists and Chemical Engineers

Mjesto i datum
Rovinj, Hrvatska, 28.03.2023. - 31.03.2023

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
pentacyanoferrate(II) complexes ; 4-imidazoline-2-thiones

Sažetak
Heterocyclic compounds based on 4-imidazoline-2- thione are especially important in medicine. They are used as inhibitors of dopamine β-hydroxylase, diuretics, anti-inflammatory and antithyroid drugs. The most commonly used drugs in the treatment of hyperthyroidism are propylthiouracil and two substituted 4-imidazoline-2-thiones, namely, methimazole and carbimazole. In addition, imidazoline-2-thiones serve as precursors in the synthesis of imidazole derivatives and various condensed heterocycles. In the coordination chemistry, imidazoline-2-thiones are important and versatile N, S-donor ligands. In the investigations of reactivity and coordination ability of ambidentate ligands, aquapentacyanoferrate(II) has proven useful. The [Fe(CN)5(OH2)]3–, a structural model of biologically important octahedral iron(II) complexes, undergoes the water–ligand exchange reaction producing corresponding pentacyano(ligand)ferrates(II). The ligand substitution reactions of aquapentacyanoferrate(II) ion with 4-imidazoline- 2-thione (imtH2), 1-methyl-4-imidazoline-2-thione (meimtH, methimazole) or ethyl 3-methyl-2- sulfanylidene-imidazole-1-carboxylate (meimtR, carbimazole) were studied in aqueous solutions. The produced pentacyano(imidazoline-2- thione)ferrates(II) were characterized by UV/Vis and 13C-NMR spectroscopy. The equilibrium constant for the formation of pentacyano(imidazoline-2-thione)ferrate(II) was determined spectrophotometrically. The rate constants and activation parameters for the formation as well as for the dissociation of pentacyano(imidazoline-2-thione)ferrate(II) complexes were determined by UV/Vis spectroscopy. The hydrolysis of free meimtR and meimtR coordinated on [Fe(CN)5]3– moiety was investigated. On the basis of spectroscopic data and kinetic parameters it has been established that 4-imidazoline-2-thiones coordinate to iron(II) through the sulfur atom.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Zagreb


Citiraj ovu publikaciju:

Damjanović, Vladimir; Musija, Danijela; Picek, Igor; Foretić, Blaženka
Equilibrium and kinetic studies on the reactions of aquapentacyanoferrate(II) with 4-imidazoline-2- thiones // 28th Croatian Meeting of Chemists and Chemical Engineers: Book of Abstracts / Rogošić, Marko (ur.).
Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2023. str. 68-68 (poster, domaća recenzija, sažetak, znanstveni)
Damjanović, V., Musija, D., Picek, I. & Foretić, B. (2023) Equilibrium and kinetic studies on the reactions of aquapentacyanoferrate(II) with 4-imidazoline-2- thiones. U: Rogošić, M. (ur.)28th Croatian Meeting of Chemists and Chemical Engineers: Book of Abstracts.
@article{article, author = {Damjanovi\'{c}, Vladimir and Musija, Danijela and Picek, Igor and Foreti\'{c}, Bla\v{z}enka}, editor = {Rogo\v{s}i\'{c}, M.}, year = {2023}, pages = {68-68}, keywords = {pentacyanoferrate(II) complexes, 4-imidazoline-2-thiones}, title = {Equilibrium and kinetic studies on the reactions of aquapentacyanoferrate(II) with 4-imidazoline-2- thiones}, keyword = {pentacyanoferrate(II) complexes, 4-imidazoline-2-thiones}, publisher = {Hrvatsko dru\v{s}tvo kemijskih in\v{z}enjera i tehnologa (HDKI)}, publisherplace = {Rovinj, Hrvatska} }
@article{article, author = {Damjanovi\'{c}, Vladimir and Musija, Danijela and Picek, Igor and Foreti\'{c}, Bla\v{z}enka}, editor = {Rogo\v{s}i\'{c}, M.}, year = {2023}, pages = {68-68}, keywords = {pentacyanoferrate(II) complexes, 4-imidazoline-2-thiones}, title = {Equilibrium and kinetic studies on the reactions of aquapentacyanoferrate(II) with 4-imidazoline-2- thiones}, keyword = {pentacyanoferrate(II) complexes, 4-imidazoline-2-thiones}, publisher = {Hrvatsko dru\v{s}tvo kemijskih in\v{z}enjera i tehnologa (HDKI)}, publisherplace = {Rovinj, Hrvatska} }




Contrast
Increase Font
Decrease Font
Dyslexic Font