Pregled bibliografske jedinice broj: 1264831
Intra-Species Variations of Bioactive Compounds of Two Dictyota Species from the Adriatic Sea: Antioxidant, Antimicrobial, Dermatological, Dietary, and Neuroprotective Potential
Intra-Species Variations of Bioactive Compounds of Two Dictyota Species from the Adriatic Sea: Antioxidant, Antimicrobial, Dermatological, Dietary, and Neuroprotective Potential // Antioxidants, 12 (2023), 857, 30 doi:10.3390/antiox12040857 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1264831 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Intra-Species Variations of Bioactive Compounds of
Two Dictyota Species from the Adriatic Sea: Antioxidant, Antimicrobial, Dermatological, Dietary, and Neuroprotective Potential
Autori
Martić, Ana ; Čižmek, Lara ; Ul’yanovskii, Nikolay V. ; Paradžik, Tina ; Perković, Lucija ; Matijević, Gabrijela ; Vujović, Tamara ; Baković, Marija ; Babić, Sanja ; Kosyakov, Dmitry S. ; Trebše, Polonca ; Čož-Rakovac, Rozelindra
Izvornik
Antioxidants (2076-3921) 12
(2023);
857, 30
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Dictyota dichotoma ; Dictyota fasciola ; Brown seaweeds ; Chromatography ; Toxicity ; Proteins ; Carbohydrates ; Amino acids ; Bioactivity
Sažetak
The marine environment has a significant impact on life on Earth. Organisms residing in it are vital for the ecosystem but also serve as an inexhaustible source of biologically active compounds. Herein, the biodiversity of two brown seaweeds, Dictyota dichotoma and Dictyota fasciola from the Adriatic Sea, was evaluated. The aim of the study was the determination of differences in compound composition while comparing their activities, including antioxidant, antimicrobial, and enzyme inhibition, in connection to human digestion, dermatology, and neurological disorders. Chemical analysis revealed several terpenoids and steroids as dominant molecules, while fucoxanthin was the main identified pigment in both algae. D. dichotoma had higher protein, carbohydrate, and pigment content. Omega-6 and omega-3 fatty acids were identified, with the highest amount of dihomo-γ-linolenic acid and α-linolenic acid in D. dichotoma. Antimicrobial testing revealed a dose-dependent inhibitory activity of methanolic fraction against Escherichia coli and Staphylococcus aureus. Moderate antioxidant activity was observed for both algae fractions, while the dietary potential was high, especially for the D. fasciola dichloromethane fraction, with inhibition percentages of around 92% for α-amylase and 57% for pancreatic lipase at 0.25 mg/mL. These results suggest that Dictyota species might be a potent source of naturally derived agents for obesity and diabetes.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Kemijsko inženjerstvo, Biotehnologija
POVEZANOST RADA
Projekti:
EK-EFRR-KK.01.2.1.02.0095 - SUPERHRANA – Mikroalgama do inovativnih pekarskih proizvoda i tjestenine (Roje, Marin; Čož-Rakovac, Rozelinda, EK ) ( CroRIS)
EK-KF-KK.01.1.1.01.0002 - Bioprospecting Jadranskog mora (Jerković, Igor; Dragović-Uzelac, Verica; Šantek, Božidar; Čož-Rakovac, Rozelinda; Kraljević Pavelić, Sandra; Jokić, Stela, EK ) ( CroRIS)
EK-EFRR-KK.01.2.1.02.0015 - In silico procjenom bioaktivnosti mikroalgi do razvoja inovativnih biobaziranih proizvoda (Roje, Marin; Čož-Rakovac, Rozelinda, EK ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Profili:
Ana Martić
(autor)
Sanja Babić
(autor)
Gabrijela Matijević
(autor)
Tina Paradžik
(autor)
Lara Čižmek
(autor)
Tamara Vujović
(autor)
Lucija Perković
(autor)
Marija Baković
(autor)
Rozelinda Čož-Rakovac
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus