Naslov
Could initial radiological response be used to predict duration of first-line treatment in HER2 positive metastatic breast cancer?

Autori
Linarić, Petra ; Tečić Vuger, Ana ; Pavlović Mavič, Mirjana ; Vazdar, Ljubica ; Jakšić, Petra ; Šeparović, Robert

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
16th Central European Oncology Congress Book of abstract / - , 2022, 91-92

Skup
16th Central European Oncology Congress, A Best of ASCO® Meeting

Mjesto i datum
Opatija, Hrvatska, 22.06.2022. - 25.06.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
breast cancer, HER2 positive, initial radiological response to therapy

Sažetak
First-line treatment with pertuzumab/trastuzumab/docetaxel significantly improved overall survival for patients with HER2-positive metastatic breast cancer compared with placebo/trastuzumab/docetaxel. Our question is whether there is a statistically significant difference in first-line therapy duration in patients who initially, after 3 months of treatment, had tumor regression versus patients who had radiological stable disease? Statistically significant results were obtained, showing that overall duration of treatment was longer in the group of patients who initially had radiological disease regression, as opposed to the group of patients with initial stable disease verified, with 4, 5 months increase in the median values.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne tehničke znanosti, Kliničke medicinske znanosti

POVEZANOST RADA