Naslov
Encapsulation of Ground Ivy (Glechoma hederacea L.) extract, obtained by natural deep eutectic solvents extraction, in liposomes

Autori
Balanč, Bojana ; Halagi, Jelena ; Skrobonja, Jovan ; Milivojevic, Ana ; Šeremet, Danijela ; Komes, Draženka ; Pjanović, Rada

Kolaboracija
Innovation Centre, Faculty of Technology and Metallurgy, University of Belgrade, Serbia ; Faculty of Technology and Metallurgy, University of Belgrade, Serbia

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Proceedings - 10th International Congress of Food Technologists, Biotechnologists and Nutritionists / Komes, Draženka ; Vidaček Filipec, Sanja ; Voučko, Bojana - Zagreb : Hrvatsko društvo prehrambenih tehnologa, biotehnologa i nutricionista, 2022, 10-13

Skup
10th International Congress of Food Technologists, Biotechnologists and Nutritionists

Mjesto i datum
Zagreb, Hrvatska, 30.11.2022. - 02.12.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
natural deep eutectic solvents ; ground ivy ; liposomes ; sustained release

Sažetak
Ground ivy (Glechoma hederacea L.) has been used in traditional medicine for centuries. Its medicinal properties were known even by Galen, who recommended this plant to those suffering from eye diseases. It contains flavonoids (quercetin, apigenin and luteolin), phenolic acids (rosmarinic, caffeic), tannins, sesquiterpenes, bitter substances, a little essential oil, saponin and resin. In the present study extraction of ground ivy was performed using different natural deep eutectic solvents mixtures (NDES). For those purposes several different NDESs was used and results show that best eutectic mixture for ground ivy extraction is betain and citric acid in molar ratio 1:1. Extraction was carried at room temperature and yield of rosmarinic and caffeic acid is significantly higher comparing with water extraction at 80oC. Extracts were encapsulated in liposomes prepared using proliposome and thin film methods, following by sonication to obtain smaller, more stable particles. Encapsulation should preserve actives from external factors such as oxidation, hydrolyzes, temperature degradation etc. The release of ground ivy extract from liposomes was studied using standard Franz diffusion cell. The results show that the release of the extract is slowest from liposomes prepared by the proliposome method, but all systems give satisfactory sustained release.

Izvorni jezik
Engleski

Znanstvena područja
Prehrambena tehnologija

POVEZANOST RADA