Pregled bibliografske jedinice broj: 1262161
HIF-1α immunohistochemical expression in decidual cells, villous and extravillous trophoblast in placentas from pregnancies complicated with preeclampsia
HIF-1α immunohistochemical expression in decidual cells, villous and extravillous trophoblast in placentas from pregnancies complicated with preeclampsia // Pregnancy Hypertension, 21 (2020), 176-178 doi:10.1016/j.preghy.2020.06.003 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1262161 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
HIF-1α immunohistochemical expression in decidual cells, villous and extravillous trophoblast in placentas from pregnancies complicated with preeclampsia
Autori
Kosović, Indira ; Prusac-Kuzmić, Ivana ; Meštrović, Zoran ; Berkovic, A. ; Marušić, Jelena ; Tomaš-Zekić, Sandra
Izvornik
Pregnancy Hypertension (2210-7789) 21
(2020);
176-178
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
decidual cells ; extravillous trophoblast ; HIF-1α ; preeclampsia ; villous trophoblast
Sažetak
Etiology of preeclampsia (PE) remains unknown despite it being the leading cause of maternal and neonatal morbidity and mortality worldwide. PE placentas show signs of chronic oxidative stress, therefore we set to investigate the HIF-1α immunohistochemical expression in PE placentas. For the first time presented study reported on significantly higher HIF-1α immunohistochemical expression in all of the placental segments ; villous trophoblast (VTB), decidual cells (DC) and extravillous trophoblast (EVTB) in the PE placentas compared to placentas from normal pregnancies. The further studies on the subject are necessary in order to understand the mechanisms behind elevated HIF-1α immunohistochemical levels in PE.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
KBC Split,
Medicinski fakultet, Split
Profili:
Ivana Kuzmić-Prusac
(autor)
Indira Kosović
(autor)
Jelena Marušić
(autor)
Sandra Zekić-Tomaš
(autor)
Zoran Meštrović
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE