Naslov
The effect of botulinum toxin type A in patients with essential blepharospasm

Autori
Gaćina, Klara ; Lešin, Mladen ; Sarajčev, Dean ; Rotim, Nina

Izvornik
Acta clinica Croatica (0353-9466) 61 (2022), 3; 379-385

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
botilinum toxin type A ; essencial blepharospasm ; dystonia ; Blepharospasm Disability Index ; Jankovic Rating Scale

Sažetak
The aim of this study was to determine the effect of botulinum toxin type A and satisfaction in patients with essential blepharospasm. The study included 12 subjects suffering from essential blepharospasm who received therapy with botulinum toxin type A injections. Respondents were given a Blepharospasm Disability Index (BSDI) survey before and three weeks after the procedure with questions related to quality of life. They were also given a Jankovic Rating Scale with questions related to the severity and frequency of symptoms. The overall level of difficulties was reduced, mean- ing the quality of life increased after the application of botulinum toxin, and the study found that the increase was statistically significant (p = 0.003). The severity of symptoms after the application of botulinum toxin was reduced, which meant that there was a decrease in the severity of the difficulties, and the study found a statistically significant difference (p=0.003). The frequency of symptoms was reduced after botulinum toxin administration, and the study revealed a statistically significant dif- ference (p = 0.012). From the results of this study, we can determine that the use of botulinum toxin type A increases the quality of life and that the severity and frequency of symptoms are statistically significantly reduced.

Izvorni jezik
Engleski

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