Stress and reproductive hormones in hair associated with contaminant metal(loid)s of European brown bear (Ursus arctos)

Lazarus, Maja; Sergiel, Agnieszka; Ferenčaković, Maja; Orct, Tatajana; Kapronczai, Luciene; Pađen, Lana; Janz, David M; Reljić, Slaven; Zwijacz-Kozica, Tomasz; Zieba, Filip; Selva, Nuria; Huber, Đuro

doi:10.1016/j.chemosphere.2023.138354

Pregled bibliografske jedinice broj: 1261116

Stress and reproductive hormones in hair associated with contaminant metal(loid)s of European brown bear (Ursus arctos)

Lazarus, Maja; Sergiel, Agnieszka; Ferenčaković, Maja; Orct, Tatajana; Kapronczai, Luciene; Pađen, Lana; Janz, David M; Reljić, Slaven; Zwijacz-Kozica, Tomasz; Zieba, Filip et al.

Stress and reproductive hormones in hair associated with contaminant metal(loid)s of European brown bear (Ursus arctos) // Chemosphere, 325 (2023), 1-9 doi:10.1016/j.chemosphere.2023.138354 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1261116 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Stress and reproductive hormones in hair associated with contaminant metal(loid)s of European brown bear (Ursus arctos)

Autori
Lazarus, Maja ; Sergiel, Agnieszka ; Ferenčaković, Maja ; Orct, Tatajana ; Kapronczai, Luciene ; Pađen, Lana ; Janz, David M ; Reljić, Slaven ; Zwijacz-Kozica, Tomasz ; Zieba, Filip ; Selva, Nuria ; Huber, Đuro

Izvornik
Chemosphere (0045-6535) 325 (2023); 1-9

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cortisol ; progesterone ; testosterone ; potentially toxic metal ; endocrine disrupting chemical

Sažetak
Environmental contaminants like arsenic (As), cadmium (Cd), mercury (Hg) or lead (Pb) may disrupt hypothalamic–pituitary–adrenal (HPA) and hypothalamic-pituitary-gonadal (HPG) axes due to their endocrine toxicity potential. Resulting long-term physiological stress or adverse effects on wildlife reproduction and ontogeny may cause detrimental effects at the individual and population levels. However, data on environmental metal(loid)sʼ impact on reproductive and stress hormones in wildlife, especially large terrestrial carnivores, are scarce. Hair cortisol, progesterone and testosterone concentrations were quantified and modelled with hair As, Cd, total Hg, Pb, biological, environmental and sampling factors to test for potential effects in free- ranging brown bears (Ursus arctos) from Croatia (N=46) and Poland (N=27). Testosterone in males (N=48) and females (N=25) showed positive associations with Hg and an interaction between Cd and Pb, but a negative association with interaction between age and Pb. Higher testosterone was found in hair during its growth phase compared to quiescent phase. Body condition index was negatively associated with hair cortisol and positively associated with hair progesterone. Year and conditions of sampling were important for cortisol variation, while maturity stage for progesterone variation (lower concentrations in cubs and yearlings compared to subadult and adult bears). These findings suggest that environmental levels of Cd, Hg and Pb might influence the HPG axis in brown bears. Hair was shown to be a reliable non-invasive sample for investigating hormonal fluctuations in wildlife while addressing individual and sampling specificities.

Izvorni jezik
Engleski

Znanstvena područja
Interdisciplinarne prirodne znanosti, Javno zdravstvo i zdravstvena zaštita, Veterinarska medicina

POVEZANOST RADA

Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb,
Veterinarski fakultet, Zagreb,
Agronomski fakultet, Zagreb

Profili:

Lana Pađen (autor)