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Pregled bibliografske jedinice broj: 1260542

Prostate cancer - focus on cholesterol

Škara, Lucija; Huđek Turković, Ana; Pezelj, Ivan; Vrtarić, Alen; Sinčić, Nino; Krušlin, Božo; Ulamec, Monika
Prostate cancer - focus on cholesterol // Cancers, 13 (2022), 18; 4696, 22 doi:10.3390/cancers13184696 (međunarodna recenzija, pregledni rad, znanstveni)

CROSBI ID: 1260542 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Prostate cancer - focus on cholesterol

Autori
Škara, Lucija ; Huđek Turković, Ana ; Pezelj, Ivan ; Vrtarić, Alen ; Sinčić, Nino ; Krušlin, Božo ; Ulamec, Monika

Izvornik
Cancers (2072-6694) 13 (2022), 18; 4696, 22

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
AR ; PTEN ; SREBP2 ; cholesterol ; mTOR: MAP ; p53 ; prostate cancer

Sažetak
Prostate cancer (PC) is the most common malignancy in men. Common characteristic involved in PC pathogenesis are disturbed lipid metabolism and abnormal cholesterol accumulation. Cholesterol can be further utilized for membrane or hormone synthesis while cholesterol biosynthesis intermediates are important for oncogene membrane anchoring, nucleotide synthesis and mitochondrial electron transport. Since cholesterol and its biosynthesis intermediates influence numerous cellular processes, in this review we have described cholesterol homeostasis in a normal cell. Additionally, we have illustrated how commonly deregulated signaling pathways in PC (PI3K/AKT/MTOR, MAPK, AR and p53) are linked with cholesterol homeostasis regulation.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)



POVEZANOST RADA

Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice"

Profili:

Avatar Url Monika Ulamec (autor)

Avatar Url Nino Sinčić (autor)

Avatar Url Ana Huđek Turković (autor)

Avatar Url Alen Vrtarić (autor)

Avatar Url Lucija Škara (autor)

Avatar Url Božo Krušlin (autor)

Poveznice na cjeloviti tekst rada:

doi

Citiraj ovu publikaciju:

Škara, Lucija; Huđek Turković, Ana; Pezelj, Ivan; Vrtarić, Alen; Sinčić, Nino; Krušlin, Božo; Ulamec, Monika
Prostate cancer - focus on cholesterol // Cancers, 13 (2022), 18; 4696, 22 doi:10.3390/cancers13184696 (međunarodna recenzija, pregledni rad, znanstveni)
Škara, L., Huđek Turković, A., Pezelj, I., Vrtarić, A., Sinčić, N., Krušlin, B. & Ulamec, M. (2022) Prostate cancer - focus on cholesterol. Cancers, 13 (18), 4696, 22 doi:10.3390/cancers13184696.
@article{article, author = {\v{S}kara, Lucija and Hu\djek Turkovi\'{c}, Ana and Pezelj, Ivan and Vrtari\'{c}, Alen and Sin\v{c}i\'{c}, Nino and Kru\v{s}lin, Bo\v{z}o and Ulamec, Monika}, year = {2022}, pages = {22}, DOI = {10.3390/cancers13184696}, chapter = {4696}, keywords = {AR, PTEN, SREBP2, cholesterol, mTOR: MAP, p53, prostate cancer}, journal = {Cancers}, doi = {10.3390/cancers13184696}, volume = {13}, number = {18}, issn = {2072-6694}, title = {Prostate cancer - focus on cholesterol}, keyword = {AR, PTEN, SREBP2, cholesterol, mTOR: MAP, p53, prostate cancer}, chapternumber = {4696} }
@article{article, author = {\v{S}kara, Lucija and Hu\djek Turkovi\'{c}, Ana and Pezelj, Ivan and Vrtari\'{c}, Alen and Sin\v{c}i\'{c}, Nino and Kru\v{s}lin, Bo\v{z}o and Ulamec, Monika}, year = {2022}, pages = {22}, DOI = {10.3390/cancers13184696}, chapter = {4696}, keywords = {AR, PTEN, SREBP2, cholesterol, mTOR: MAP, p53, prostate cancer}, journal = {Cancers}, doi = {10.3390/cancers13184696}, volume = {13}, number = {18}, issn = {2072-6694}, title = {Prostate cancer - focus on cholesterol}, keyword = {AR, PTEN, SREBP2, cholesterol, mTOR: MAP, p53, prostate cancer}, chapternumber = {4696} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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