Naslov
Impact of reduced creatinine clearance on early heart transplantation outcomes: A propensity score adjusted analysis

Autori
Gašparović, Hrvoje ; Unić, Daniel ; Svetina, Lucija ; Samardžić, Jure ; Čikeš, Maja ; Baričević, Željko ; Skorić, Boško ; Kopjar, Tomislav ; Anić, Darko ; Ivančan, Višnja ; Sutlić, Željko ; Biočina, Bojan ; Miličić, Davor

Izvornik
International journal of cardiology (0167-5273) 203 (2016); 50-52

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Heart transplantation ; Renal failure ; Outcome

Sažetak
Heart transplantation (HTx) remains the unsurpassed standard of care for end-stage congestive heart failure (HF). HTx outcomes are benchmarks against which key outcome metrics of alternative lines of advanced HF management are compared to. Postoperative renal failure in non-renal solid organ transplant recipients leads to a fourfold increase in mortality. Many perioperative factors converge to adversely affect renal function. These include preoperative renal dysfunction, suboptimal hemodynamics, and calcineurin inhibitor therapy. Moreover, multiple comorbidities common to HTx candidates, such as hypertension and diabetes mellitus, act in concert to compromise renal function.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA