Naslov
Subtyping of triple-negative breast cancer

Autori
Ramić, Snježana ; Cesarec Augustinović, Sanja ; Puhalo, Ana ; Karačić, Ena ; Perić Balja, Melita

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Libri Oncologici : Croatian Journal of Oncology, Vol. 50 No. Supplement 1, 2022. / - , 2022, 145-145

Skup
15. Hrvatski onkološki kongres

Mjesto i datum
Opatija, Hrvatska, 31.03.2022. - 03.04.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
triple-negative breast cancer, subtypes, androgen receptor, CK5/14, EGFR, PD-L1

Sažetak
Recent researches show a high heterogeneity of triple-negative breast cancers (TNBC).Subtyping of TNBC would better select patients for different therapeutic approaches.That would ensure proper treatment in the early stages of cancer, which increases the effectiveness of treatment and better control of the disease.Based on the expression of AR, CK5/14, EGFR, and PDL1, we cannot fully classify TNBC.However, determining the underlying subgroup (basal-like or luminal) and the expression of markers that may have therapeutic significance (EGFR, PD-L1) stratify patients suitable for tailoredtherapeutic options.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA