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Pregled bibliografske jedinice broj: 1259349

Epigenetics and testicular germ cell tumors

Buljubašić, Robert; Buljubašić, Maja; Katušić Bojanac, Ana; Ulamec, Monika; Vlahović, Maja; Ježek, Davor; Bulić-Jakuš, Floriana; Sinčić, Nino
Epigenetics and testicular germ cell tumors // Gene, 661 (2018), 22-33 doi:10.1016/j.gene.2018.03.072 (međunarodna recenzija, pregledni rad, znanstveni)

CROSBI ID: 1259349 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Epigenetics and testicular germ cell tumors

Autori
Buljubašić, Robert ; Buljubašić, Maja ; Katušić Bojanac, Ana ; Ulamec, Monika ; Vlahović, Maja ; Ježek, Davor ; Bulić-Jakuš, Floriana ; Sinčić, Nino

Izvornik
Gene (0378-1119) 661 (2018); 22-33

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
testicular cancer ; mutation ; epimutation ; biomarker ; therapy

Sažetak
Malignant testicular germ cell tumors (TGCTs) are the most frequent testicular cancers in Caucasian males, developing at the most productive age of man. We are briefly reviewing TGCT-tumorigenesis with an emphasis on epigenetics. Epigenetic mechanisms such as DNA methylation and histone modifications together with RNA interference that all change gene expression are driving early spermatogenesis. Deregulation of normal development might lead to a testicular germ cell neoplasia in situ (GCNIS), from which TGCTs originate. The breakthrough epigenetic research, both in normal development and TGCT tumorigenesis, has been going on to find better biomarkers and therapy for this type of tumors.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA

Projekti:
--KK.01.1.1.01.0008 - Znanstveni centar izvrsnosti za reproduktivnu i regenerativnu medicinu – istraživanja novih platormi i potencijala (CERRM) (Ježek, Davor; Vukičević, Slobodan) ( CroRIS)

Ustanove:
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Klinička bolnica "Dubrava"

Profili:

Avatar Url Floriana Jakuš (autor)

Avatar Url Nino Sinčić (autor)

Avatar Url Maja Vlahović (autor)

Avatar Url Maja Buljubašić (autor)

Avatar Url Davor Ježek (autor)

Avatar Url Ana Katušić Bojanac (autor)

Avatar Url Monika Ulamec (autor)

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi pubmed.ncbi.nlm.nih.gov

Citiraj ovu publikaciju:

Buljubašić, Robert; Buljubašić, Maja; Katušić Bojanac, Ana; Ulamec, Monika; Vlahović, Maja; Ježek, Davor; Bulić-Jakuš, Floriana; Sinčić, Nino
Epigenetics and testicular germ cell tumors // Gene, 661 (2018), 22-33 doi:10.1016/j.gene.2018.03.072 (međunarodna recenzija, pregledni rad, znanstveni)
Buljubašić, R., Buljubašić, M., Katušić Bojanac, A., Ulamec, M., Vlahović, M., Ježek, D., Bulić-Jakuš, F. & Sinčić, N. (2018) Epigenetics and testicular germ cell tumors. Gene, 661, 22-33 doi:10.1016/j.gene.2018.03.072.
@article{article, author = {Buljuba\v{s}i\'{c}, Robert and Buljuba\v{s}i\'{c}, Maja and Katu\v{s}i\'{c} Bojanac, Ana and Ulamec, Monika and Vlahovi\'{c}, Maja and Je\v{z}ek, Davor and Buli\'{c}-Jaku\v{s}, Floriana and Sin\v{c}i\'{c}, Nino}, year = {2018}, pages = {22-33}, DOI = {10.1016/j.gene.2018.03.072}, keywords = {testicular cancer, mutation, epimutation, biomarker, therapy}, journal = {Gene}, doi = {10.1016/j.gene.2018.03.072}, volume = {661}, issn = {0378-1119}, title = {Epigenetics and testicular germ cell tumors}, keyword = {testicular cancer, mutation, epimutation, biomarker, therapy} }
@article{article, author = {Buljuba\v{s}i\'{c}, Robert and Buljuba\v{s}i\'{c}, Maja and Katu\v{s}i\'{c} Bojanac, Ana and Ulamec, Monika and Vlahovi\'{c}, Maja and Je\v{z}ek, Davor and Buli\'{c}-Jaku\v{s}, Floriana and Sin\v{c}i\'{c}, Nino}, year = {2018}, pages = {22-33}, DOI = {10.1016/j.gene.2018.03.072}, keywords = {testicular cancer, mutation, epimutation, biomarker, therapy}, journal = {Gene}, doi = {10.1016/j.gene.2018.03.072}, volume = {661}, issn = {0378-1119}, title = {Epigenetics and testicular germ cell tumors}, keyword = {testicular cancer, mutation, epimutation, biomarker, therapy} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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