Naslov
Main charasteristics and trend in elderly (>50 years) persons entering HIV care in Croatia in the period from 2007 to 2017

Autori
Perović, Marta ; Bogdanić, Nikolina ; Močibob, Loris ; Lukas, Davorka ; Zekan, Šime ; Begovac, Josip

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
Međunarodni kongres: Starenje s HIV-om - pristup sveobuhvatnoj skrbi

Mjesto i datum
Zagreb, Hrvatska, 15.03.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
HIV care, Croatia

Sažetak
Introduction: In the last two decades life expectancy of person infected with HIV was prolonged, mainly due to usage of antiretroviral drugs, resulting in increased number of HIV + elderly (>50 years) people. Considering the complexity of health in elderly providing care for that population can be challenging. The aim of our study was to describe characteristics and trends in persons older than 50 years who entered HIV care for the first time in Zagreb, Croatia in period 2007 to 2017. Methods: This study included elderly (>50 years) persons who have never been in HIV care elsewhere in the period from January 2007 do December 2017. Descriptive statistics was used for categorical and continous variables. The Mann Whitney test was used to analyze late presentation to care, CD4+ cell count and viral load across different categories of age (18 to 29, 30 to 39, 40 to 49, and >50 years). Results were analyzed with SAS version 9.4, and Joinpoint software was used to assess the trend in the rate of males entering HIV care from 2007 to 2016. Results: Among 882 adults (>18 years) who entered HIV care from 2007 to 2017, 99 (11.2%) were older that 50 years (median: 54.9 years). Elderly patients were mstly male (91.9%), not residents of the Zagreb area (71.7%), and man who have sex with men (62.6%). When compared to the other age groups the median CD4+ T-cell count was the lowest (121 per mm3) and the viral load was highest (median 251 188 copies/mL) among elderly persons. The proportion of persons with cd4+ T-cell counts below 200/mm3 (62.6) and with viral load >100 000 HIV1 RNA/mL was highest (68.7%) in the age group of >50 years. The highest proportions of late and very late presenters were found in elderly (83.8%) and 62.6%, respectively). Rates per 100 000 inhabitants of HIV+ men and elderly HIV+ men who entered care increased significantly in the observed period (from 2.36 in 2007 to 4.65 in 2016 for all males p<.001 ; and from 0.85 in 2007 to 1.85 in 2016 for elderly males, p=0.019). Conclusions: We found an increase in rates of HIV infections in men of all ages in the period 2007 to 2016, including an increasing rate in elderly HIV+ men. Elderly person presented with more severe clinical manifestations, lower CD4+ T-cell counts, and higher viral loads when compared to the ozher age groups. Efforts should be undertaken for erlier HIV diagnosis in elderly persons.

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti

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