Naslov
Prevalence of prediabetes, diabetes and obesity in HIV infected persons in Croatia, 2016 to 2020

Autori
Begovac, Josip ; Benković, Ivana ; Zekan, Šime ; Lukas, Davorka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
18th European AIDS Conference

Mjesto i datum
Online, 27.10.2021. - 30.10.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
prevalence ; obesity ; diabetes ; HIV patients ; Croatia

Sažetak
To describe the trend in prevalence prediabetes, type 2 diabetes mellitus (T2DM) and obesity among people living with HIV (PLHIV) in Croatia from 2016 to 2020 and evaluate factors related to prediabetes and T2DM. We included HIV-infected persons > 18 years old residing in Croatia and receiving care at the only HIV treatment centre in Croatia in the period 2016-2020. Prediabetes and T2DM were defined based on fasting plasma glucose, according to the American Diabetes Association (ADA, fasting plasma glucose 5.6 to 6.9 mmol/L and fasting plasma glucose ≥ 7.0 mmol/L respectively) and WHO definitions (prediabetes: fasting plasma glucose 6.1 to 6.9 mmol/L). Multinomial logistic regression of factors associated with prediabetes and diabetes was done. We analysed 1419 patients, females 139 (9.7%) and median age was 43.7 years. The overall prevalence of prediabetes was 47.4% (95% CI, 44.8-50.1% ) (ADA definition), 21.6% (95% CI, 19.5-23.9%) (WHO definition) and of T2DM it was 6.9% (95% CI, 5.6- 8.4%). There was no change in the yearly point prevalence of prediabetes and T2DM in the period 2016-2020. There was an increase in the prevalence of obesity (9.9%, 94/951 in 2016 and 14.3%, 154/1077) and overweight (40.3%, 383/951 in 2016 and 43.3%, 466/1077) in the period 2016 to 2020 (P-value for trend 0.02). The number of persons ≥50 years old in care increased from 29.1% in 2016 to 34.3% in 2020. The major factor related to the prevalence of T2DM and prediabetes were age and duration of HIV-infection. Other factors related to the prevalence of T2DM were hypertension, higher body mass index and serum triglycerides. We found a high prevalence of prediabetes in the HIV population in Croatia. As the population of HIV infected persons is aging early lifestyle interventions to reduce the risk of TD2M are needed.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA