Naslov
Clinical characteristics and treatment outcome of patients with sepsis treated in an infectious disease intensive care unit

Autori
Novak, Rafaela ; Popović, Marta ; Baršić, Bruno ; Santini, Marija ; Kutleša, Marko ; Krajinović, Vladimir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
30th ECCMID 2020

Mjesto i datum
Pariz, Francuska, 18.04.2020. - 21.04.2020

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Clinical characteristics ; treatment ; sepsis ; treatment ; intensive care unit

Sažetak
Background: In most countries of the European Union patients suffering from sepsis are commonly treated in general intensive care units (ICU). By contrast, in some European countries, as well as in Zagreb, Croatia, these patients are admitted to a specialized infectious disease intensive care unit (IDICU). The study aimed to evaluate the clinical and epidemiological features of patients with severe sepsis admitted to an IDICU and compare treatment outcome in IDICU with literature data on the outcome of patients admitted to a non- IDICU. Materials/methods: This research is a retrospective data analysis on 408 patients with the diagnosis of sepsis admitted to the 18-bed IDICU of the University Hospital for Infectious Diseases in Zagreb, Croatia over a three year period (January 2016 to December 2018). Results: The admitting diagnosis of sepsis represented 35% of all admitting diagnoses in the IDICU. Nearly 2/3 of admitted patients with sepsis were men and the age median was 65 (IQR 55-75), whereas the median of Charlson Comorbidity Index (CCI) was 3 (IQR 2-5). Septic shock was present in 40% of patients, while the median of Sequential Organ Failure Assessment Score (SOFA) was 7 (IQR 4-11). In the IDICU the median patient length of stay was 8 (IQR 3-19) days. The most commonly associated infections were neurological (16%), endocarditis (15%) and urinary tract infections (12%). The specific mortality rate among patients with sepsis was 14%. Around 10% of admitted patients with sepsis were discharged from the IDICU as independent and mobile, while 23% of patients were left with reduced functional disability and 27% of patients were completely dependent and immobile, with case fatality rate of 40%. Conclusions: The proportion of admitted patients with sepsis in the IDICU was 35%, which is higher than in other ICU-s in Croatia (10-20%) according to literature. The specific mortality rate of IDICU patients of 14% was though in the lower portion of the compared specific mortality range for sepsis (10-50%). Taken into consideration that the admitted patients had higher CCI and SOFA scores, we observed that the type of ICU may have had an impact on the treatment outcome.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA