Surveillance of Tahyna orthobunyavirus in urban areas in Croatia — the “One Health” approach

Stevanović, Vladimir; Vilibić-Čavlek, Tatjana; Savić, Vladimir; Klobučar, Ana; Kovač, Snježana; Curman Posavec, Marcela; Petrinić, Sunčica; Bogdanić, Maja; Santini, Marija; Tešic, Vanja; de Albuquerque Soares, Nathalia; Barbić, Ljubo

doi:10.3390/tropicalmed7100320

Pregled bibliografske jedinice broj: 1257571

Surveillance of Tahyna orthobunyavirus in urban areas in Croatia — the “One Health” approach

Stevanović, Vladimir; Vilibić-Čavlek, Tatjana; Savić, Vladimir; Klobučar, Ana; Kovač, Snježana; Curman Posavec, Marcela; Petrinić, Sunčica; Bogdanić, Maja; Santini, Marija; Tešic, Vanja et al.

Surveillance of Tahyna orthobunyavirus in urban areas in Croatia — the “One Health” approach // Tropical medicine and infectious disease, 7 (2022), 10; 320, 11 doi:10.3390/tropicalmed7100320 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1257571 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Surveillance of Tahyna orthobunyavirus in urban areas in Croatia — the “One Health” approach

Autori
Stevanović, Vladimir ; Vilibić-Čavlek, Tatjana ; Savić, Vladimir ; Klobučar, Ana ; Kovač, Snježana ; Curman Posavec, Marcela ; Petrinić, Sunčica ; Bogdanić, Maja ; Santini, Marija ; Tešic, Vanja ; de Albuquerque Soares, Nathalia ; Barbić, Ljubo

Izvornik
Tropical medicine and infectious disease (2414-6366) 7 (2022), 10; 320, 11

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Croatia ; One Health ; Tahyna orthobunyavirus ; horses ; humans ; mosquitoes ; pet animals

Sažetak
Background: Tahyna orthobunyavirus (TAHV) is a neglected mosquito-borne bunyavirus. Although the virus is widespread in continental Europe, TAHV infections are rarely reported. We analyzed the prevalence of TAHV in humans and different animal species as well as mosquitoes collected in urban areas of Zagreb and its surroundings in the period from 2020 to 2022. Methods: The study included 32 patients with neuroinvasive disease (NID), 218 asymptomatic individuals, 98 horses, 94 pet animals (dogs and cats), and 4456 Aedes vexans mosquitoes. Cerebrospinal fluid (CSF) and urine samples of patients with NID were tested for the TAHV RNA using a real-time reverse transcription-polymerase chain reaction (RT-qPCR). Human and animal serum samples were tested for TAHV-neutralizing (NT) antibodies using a virus-neutralization test (VNT). Mosquito pools were tested for TAHV RNA using an RT-qPCR. Results: TAHV NT antibodies were detected in 3/9.4% of patients with NID, 8/3.7% of asymptomatic individuals, 29/29.6% of horses, and 11/11.7% of pet animals. There was no difference in the seroprevalence according to age, sex, and area of residence in asymptomatic individuals. In addition, TAHV seropositivity did not differ according to age and sex in pet animals. None of the tested mosquito pools was TAHV RNA-positive. Conclusions: The presented results highlight the importance of interdisciplinary surveillance ("One Health") of this neglected viral zoonosis.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA

Ustanove:
Hrvatski zavod za javno zdravstvo,
Hrvatski veterinarski institut, Zagreb,
Veterinarski fakultet, Zagreb,
Medicinski fakultet, Rijeka,
Medicinski fakultet, Zagreb,
Nastavni zavod za javno zdravstvo "Dr. Andrija Štampar",
Klinika za infektivne bolesti "Dr Fran Mihaljević"

Profili:

Vladimir Stevanović (autor)