Naslov
Comparative estimation of inbreeding on the X chromosome in three native Croatian cattle breeds

Autori
Shihabi, Mario ; Vostry, Lubos ; Cubric-Curik, Vlatka ; Ferenčaković, Maja ; Curik, Ino

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts 58th Croatian & 18th International Symposium on Agriculture / - , 2023, 183-183

Skup
58th Croatian & 18th International Symposium on Agriculture

Mjesto i datum
Dubrovnik, Hrvatska, 11.02.2023. - 17.02.2023

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
inbreeding ; X chromosome ; cattle ; high density SNP data ; small populations

Sažetak
Estimation of inbreeding is important for the survival of genetically small populations. Therefore, the objective of this study was to i) estimate genomic inbreeding coefficients on the X chromosome in three native Croatian cattle breeds, ii) compare estimates of different genomic inbreeding coefficients on the X chromosome based on identity by descent (IBD) with those based on identity by state (IBS), and iii) analyse segmental variation in inbreeding on the X chromosome. The analysis was based on three Croatian cattle breeds (112 individuals) genotyped with the Illumina BovineHD SNP chip (777, 000 SNPs). Our analyses revealed peculiarities in the estimation of genomic X chromosome inbreeding compared to autosomal inbreeding, e.g. higher variation and higher level of inbreeding, which should not be neglected. The obtained results can be used to estimate inbreeding depression and to identify deleterious mutations related to the X chromosome. However, to obtain more general knowledge about the genomic inbreeding level of the X chromosome, more cattle breeds should be analysed.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Poljoprivreda (agronomija), Interdisciplinarne biotehničke znanosti

POVEZANOST RADA