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Pregled bibliografske jedinice broj: 1255877

Ecotoxicological assessment of the impact of cardiovascular pharmaceuticals present in aquatic ecosystems on zebrafish embryos Danio rerio (Hamilton, 1822)


Matijević Gabrijela; Babić Sanja; Klobučar Göran;
Ecotoxicological assessment of the impact of cardiovascular pharmaceuticals present in aquatic ecosystems on zebrafish embryos Danio rerio (Hamilton, 1822) // Chem2Change, Environmental Chemistry towards Global Change, 2nd Online ACE Seminar on Chemistry and the Environment Led by Early-Career Scientists : Book of abstracts / Niemi, Lydia ; Pap, Szabolcs ; Prosenc, Franja ; Šunta, Urška ; Mišikova, Frederika ; Krejčova, Anna ; Tykva, Marek ; Gajica, Gordana ; Savić, Slađana (ur.).
Pardubice: University of Pardubice, 2022. str. 33-33 (predavanje, međunarodna recenzija, sažetak, znanstveni)


CROSBI ID: 1255877 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Ecotoxicological assessment of the impact of cardiovascular pharmaceuticals present in aquatic ecosystems on zebrafish embryos Danio rerio (Hamilton, 1822)

Autori
Matijević Gabrijela ; Babić Sanja ; Klobučar Göran ;

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Chem2Change, Environmental Chemistry towards Global Change, 2nd Online ACE Seminar on Chemistry and the Environment Led by Early-Career Scientists : Book of abstracts / Niemi, Lydia ; Pap, Szabolcs ; Prosenc, Franja ; Šunta, Urška ; Mišikova, Frederika ; Krejčova, Anna ; Tykva, Marek ; Gajica, Gordana ; Savić, Slađana - Pardubice : University of Pardubice, 2022, 33-33

ISBN
978-80-7560-406-4

Skup
Chem2Change: Environmental Chemistry Towards Global Change

Mjesto i datum
Ljubljana, Slovenija, 15.03.2022. - 16.03.2022

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cardiovascular drugs ; zebrafish embryo

Sažetak
The process of environmental pollution is experiencing exponential and unstoppable growth and has become one of the biggest problems facing humanity today. Progress in science has also brought a new type of pollution, therapeutic drugs, or pharmaceutically active compounds that are one of the main components of inland water pollution and that have been found in the sediment and plasma of fish from the Sava River. Based on previous research, cardiovascular drugs have been chosen: amiodarone, ramipril, simvastatin and verapamil, the effect of which has been investigated, individually and in a mixture, on the development of the zebrafish embryo Danio rerio (Hamilton, 1822) in the first 96 hpf. During exposure to environmentally relevant concentrations (0.1, 1.0 and 10.0 μg/L), caused changes such as mortality and abnormality rate, larval length, hatching rate, heart rate, spontaneous movements of the pectoral fins and oxidative stress were monitored. With increasing concentration and time exposure of individuals to the tested compounds, effects on exposure to all compounds were observed, but the highest toxicity was observed on the simvastatin sample. The integration of the ultimate biological effects examined within this study confirmed the excellent cause-and-effect relationship between exposure to pharmaceutical compounds and the observed effect on the aquatic organism, thus providing a basis for biomonitoring of environmental pollution, especially freshwater ecosystems.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Biotehnologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)



POVEZANOST RADA


Projekti:
EK-EFRR-KK.01.2.1.02.0095 - SUPERHRANA – Mikroalgama do inovativnih pekarskih proizvoda i tjestenine (Roje, Marin; Čož-Rakovac, Rozelinda, EK ) ( CroRIS)
EK-KF-KK.01.1.1.01.0002 - Bioprospecting Jadranskog mora (Jerković, Igor; Dragović-Uzelac, Verica; Šantek, Božidar; Čož-Rakovac, Rozelinda; Kraljević Pavelić, Sandra; Jokić, Stela, EK ) ( CroRIS)
EK-EFRR-KK.01.2.1.02.0015 - In silico procjenom bioaktivnosti mikroalgi do razvoja inovativnih biobaziranih proizvoda (Roje, Marin; Čož-Rakovac, Rozelinda, EK ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Gabrijela Matijević (autor)

Avatar Url Sanja Babić (autor)

Avatar Url Goran Klobučar (autor)

Poveznice na cjeloviti tekst rada:

eshop.upce.cz

Citiraj ovu publikaciju:

Matijević Gabrijela; Babić Sanja; Klobučar Göran;
Ecotoxicological assessment of the impact of cardiovascular pharmaceuticals present in aquatic ecosystems on zebrafish embryos Danio rerio (Hamilton, 1822) // Chem2Change, Environmental Chemistry towards Global Change, 2nd Online ACE Seminar on Chemistry and the Environment Led by Early-Career Scientists : Book of abstracts / Niemi, Lydia ; Pap, Szabolcs ; Prosenc, Franja ; Šunta, Urška ; Mišikova, Frederika ; Krejčova, Anna ; Tykva, Marek ; Gajica, Gordana ; Savić, Slađana (ur.).
Pardubice: University of Pardubice, 2022. str. 33-33 (predavanje, međunarodna recenzija, sažetak, znanstveni)
Matijević Gabrijela, Babić Sanja, Klobučar Göran & (2022) Ecotoxicological assessment of the impact of cardiovascular pharmaceuticals present in aquatic ecosystems on zebrafish embryos Danio rerio (Hamilton, 1822). U: Niemi, L., Pap, S., Prosenc, F., Šunta, U., Mišikova, F., Krejčova, A., Tykva, M., Gajica, G. & Savić, S. (ur.)Chem2Change, Environmental Chemistry towards Global Change, 2nd Online ACE Seminar on Chemistry and the Environment Led by Early-Career Scientists : Book of abstracts.
@article{article, year = {2022}, pages = {33-33}, keywords = {cardiovascular drugs, zebrafish embryo}, isbn = {978-80-7560-406-4}, title = {Ecotoxicological assessment of the impact of cardiovascular pharmaceuticals present in aquatic ecosystems on zebrafish embryos Danio rerio (Hamilton, 1822)}, keyword = {cardiovascular drugs, zebrafish embryo}, publisher = {University of Pardubice}, publisherplace = {Ljubljana, Slovenija} }
@article{article, year = {2022}, pages = {33-33}, keywords = {cardiovascular drugs, zebrafish embryo}, isbn = {978-80-7560-406-4}, title = {Ecotoxicological assessment of the impact of cardiovascular pharmaceuticals present in aquatic ecosystems on zebrafish embryos Danio rerio (Hamilton, 1822)}, keyword = {cardiovascular drugs, zebrafish embryo}, publisher = {University of Pardubice}, publisherplace = {Ljubljana, Slovenija} }




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