Naslov
The effect of continuous scuba diving on cardiovascular system

Autori
Žarak, Marko ; Perović, Antonija ; Bratičević Njire, Marina ; Goreta Supraha, Sandra ; Dumić, Jerka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
44th FEBS Congress ; From Molecules to Living Systems

Mjesto i datum
Kraków, Poland, 06.07.2019. - 11.07.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
SCUBA diving ; galectin-3 ; cardiovascular biomarkers ; myoglobin

Sažetak
Scuba diving is a special form of physical activity which due to the specific environmental conditions represents a unique stress for cardiovascular system (CVS). The aim of this study was to contribute to the understanding of changes in CVS caused by continuous scuba diving at the molecular level by monitoring the specific biochemical markers. For this purpose, 14 male divers (median age 42 years ; range 17–54) performed 5 dives (30 min to 25–30 m depth) in series with a spacing of one week between the dives. Galectin-3 (Gal-3), Vascular Endothelial Growth Factor (VEGF) and Endothelin (ET-1) (ELISA, R&D), high- sensitive Troponin-I (hs-TnI) (chemiluminiscence, Beckman Coulter), Nterminal prohormone of Brain Netriuretic Pepride (NT- proBNP) (chemiluminiscence, Abbott), myoglobin and high- sensitive Creactive protein (hs-CRP) (immunoturbidimetry, Beckman Coulter), plasma concentrations were determined in blood samples collected before and after the 1st, 3rd and 5th dive. First dive induced changes for all markers except for hs-CRP. Myoglobin, hs-TnI, NT-proBNP, VEGF, and Gal-3 significantly increased, while ET- 1 decreased immediately after the first dive. Third and fifth dive caused the same sgnificant changes in all markers, including the increase of hs-CRP after the dive. There was also significant changes in all biomarkers if comparing all pre- dive values ; hs-CRP, NT-proBNP and ET-1 concentrations increased significantly by every preformed dive, while myoglobin, hs-TnI, VEGF, and Gal-3 values decreased. ET-1 did not change significantly if comparing all post-dive values. This study showed that scuba diving causes the changes in specific biomarkers that reflect (patho)physiological changes in CVS after the dive. However, it is shown for the first time that contiuously performed scuba diving caused the decrease of specific biomarkers concentrations, thus highlighting possibly positive effect of diving on CVS.

Izvorni jezik
Engleski

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