Naslov
The impact of preoperative salivary urea, and superoxide dismutase activities on postoperative pain after surgical removal of the mandibular third molars

Autori
Grgić, Nino ; Perić, Berislav ; Tarle, Marko ; Perić, Ante ; Potočki, Slavica ; Pašalić, Daria

Vrsta, podvrsta
Radovi u časopisima, znanstveni

Izvornik
Acta clinica Croatica (2023)

Status rada
Prihvaćen

Ključne riječi
superoxide dismutase ; urea ; pain ; molar, third ; extractioin, tooth

Sažetak
BACKGROUND. The most frequent surgical procedure in oral surgery is the extraction of the mandibular third molars, which could be associated with postoperative complications like pain, swelling and trismus. We aimed to investigate the association of salivary urea and antioxidative enzyme activities with the intensity of postoperative pain after wisdom teeth extraction. MATERIAL AND METHODS. This cross-sectional prospective study included 66 subjects (median age 25, range 17-47). Salivary urea, and superoxide dismutase (SOD) were determined by enzymatic colorimetric tests. The questionnaire for study participants included demographic and anamnestic data as well the notification about personal experience of pain in grade 0-10 according to Visual Analog Scale (VAS).A grading 1-3 was considered as low (VAS-1), 4-6 mild (VAS-2) and -10 as severe pain (VAS-3). RESULTS. Moderate positive correlation was notified between concentration of urea and SOD activity in saliva (=0.46). Moderate negative correlations were found between urea salivary concentration and VAS grading value reported after 12 hours (=0.51). Concentrations of urea significantly differed among three VAS categories (P<0.001), while salivary SOD activities did not difere among categories. CONCLUSIONS. Preoperative salivary urea concentration and SOD activity might be associated with postsurgical pain after surgical removal of the mandibular third molars.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita, Dentalna medicina

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