Pregled bibliografske jedinice broj: 1253948
Fluorescence polarization binding characterization of dipyridamole and imatinib on alpha-1-acid glycoprotein
Fluorescence polarization binding characterization of dipyridamole and imatinib on alpha-1-acid glycoprotein // Macedonian pharmaceutical bulletin, 68 (2022), 1; 409-410 doi:10.33320/maced.pharm.bull.2022.68.03.197 (međunarodna recenzija, kratko priopcenje, znanstveni)
CROSBI ID: 1253948 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Fluorescence polarization binding characterization
of
dipyridamole and imatinib on alpha-1-acid
glycoprotein
Autori
Šeba, Tino ; Kerep, Robert ; Gabričević, Mario
Izvornik
Macedonian pharmaceutical bulletin (1409-8695) 68
(2022), 1;
409-410
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni
Ključne riječi
alpha-acid glycoprotein, plasma protein binding, FP
Sažetak
Alpha-1-acid glycoprotein (AGP) and albumin are two main plasma proteins involved in the binding and transport of many endogenous and exogenous ligands. Fluorescence polarization (FP) is a great technique for AGP drug binding characterization and can be used for other protein-ligand interactions. It is a simple mix-and-read protocol and does not require the separation of bound and free species. The choice of a fluorescent probe in FP assay is of key importance.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Farmacija
POVEZANOST RADA
Projekti:
IP-2016-06-3672 - Glikozilacija alfa kiselog glikoproteina - put prema personaliziranoj terapiji (GlycoDrugs) (Gabričević, Mario, HRZZ - 2016-06) ( CroRIS)
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
Citiraj ovu publikaciju:
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- DOAJ Directory and EBSCO Host
