Naslov
Bioinformatika - najmlađa znanost o dekodiranju najstarijeg jezika: jezika gena
(Bioinformatics - the youngest science about decoding the oldest language: the language of genes)

Autori
Juretić, Davor

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, pregledni

Knjiga
Zbornik radova - Fakultet prirodoslovno matematičkih znanosti i odgojnih područja Sveučilišta u Splitu, Split, 2003

Urednik/ci
Kosinac Zdenko

Izdavač
Prirodoslovno-matematički fakultet Sveučilišta u Splitu

Grad
Split

Godina
2003

Raspon stranica
73-92

ISBN
1334-3068

Ključne riječi
bioinformatika
(bioinformatics)

Sažetak
The goal of bioinformatics is decoding extremely old language of life, which has only four letters (4 different nucleotides in DNA/RNA), or onla 20 letters (20 natural amino acids in proteins). New software tools must be developed to reach that goal through comparison and analysis of biological sequences.In my group we developed SPLIT and GARLIC, first for the prediction of membrane protein secondary structure, and second for the visualisation of biomacromolecules with known 3D structure. These tools are freely available for on-line calculations (SPLIT), or as a source code (GARLIC), at our scientific server for bioinformatics and biophysics, the first such server in Croatia. More than 1000 laboratories from USA and other countries with highly developed modern biology used it from 1998. For this work, we prepared the database of membrane proteins in which point mutations cause genetic diseases, and used one of these proteins to illustrate the use of SPLIT and other bioinformatics tools.

Izvorni jezik
Hrvatski

Znanstvena područja
Fizika

POVEZANOST RADA