Naslov
Optoelectronic Cellular Interfaces with Nanocrystalline Organic Semiconductors

Autori
Glowacki, Eric Daniel ; Đerek, Vedran

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Symposium FL Biological, Biohybrid and Bioinspired Materials: From Electronics and Photonics to Medicine / - , 2018

Skup
8th Forum on New Materials

Mjesto i datum
Perugia, Italija, 04.06.2018. - 14.06.2018

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
organic semiconductors, nanocrystals, optoelectronics, bioelectronics

Sažetak
Optical stimulation of neurons offers spatial and temporal resolution combined with simplicity and minimal invasiveness. We focus on developing novel optoelectronic techniques in applied medicine, for selective peripheral or central nervous therapeutics, and implants such as retinal prostheses. Our approaches are based on efficient nanoscale semiconducting optoelectronic system optimized for neuronal stimulation. The devices comprise semiconducting organic nanocrystals. When illuminated in physiological solution, these semiconductor devices operate as photocapacitors transducing light pulses into localized displacement currents that are strong enough to electrically stimulate neurons with safe light intensities, one hundred times below the safe ocular limit at 660 nm. The devices are freestanding, requiring no wiring or external bias, and are stable in physiological conditions. The semiconductor layers are made using ubiquitous and nontoxic commercial pigments via simple and scalable deposition techniques. We present results on the level of single cells, cultured neural networks, explanted tissues, and preliminary in vivo experiments.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA