Naslov
Effect of Pesticide Exposure over DNA Damage in Farmers from Los Reyes, Michoacan in Mexico
(Effect of Pesticide Exposure over DNA Damage in Farmers from Los Reyes, Michoacan in Mexico)

Autori
Valencia-Quintana, Rafael ; Milić, Mirta ; Bonassi, Stefano ; Ochoa-Ocaña, Maria Antonieta ; Campos-Peña, Victoria ; Tenorio-Arvide, Maria Guadalupe ; Pérez- Flores, Guillermo Alejandro ; Sánchez-Alarcón, Juana

Kolaboracija
National Council of Science and Technology (CONACyT) through of FORDECYT-PRONACES, formerly FOINS-CONACyT (project title: biomarkers of genetic damage and health risk due to the use of pesticides in food production), with key FORDECYT-PRONACES, FOINS 2016-01 3203.

Izvornik
Toxics (2305-6304) 11 (2023), 2; 1-11

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
alkaline comet assay ; DNA damage ; protective equipment

Sažetak
In the municipality of Los Reyes, Michoacán, in Mexico, several economic activities coexist ; however, the most relevant is agriculture. It stands out as an agroindustrial center and commercial enclave in the region, suitable for the cultivation of sugar cane ; however, currently fruit growing takes first place with blackberry, raspberry and blueberry, followed by avocado, peach, strawberry and other crops. A large quantity and variety of pesticides are applied to crops, consequently the population is at constant risk. This study aimed to evaluate whether pesticides are a factor in genetic damage to agricultural workers from Los Reyes, Michoacán, using alkaline comet assay. Fifty-nine residents participated (41 workers and 18 controls). Results included confounding factors (alcohol consumption, smoking habit, gender, age, BMI, etc.) indicated a non-significant statistical difference between two groups, with higher DNA damage values in workers that was higher than the values expected in a normal healthy unexposed population. It seems that the control measures, safe handling of pesticides and quality standards, required by the producers so that their products can be exported, have resulted in less damage, despite workers’activity, but higher damage than the reference values still requires regular surveillance of those exposed. The use of protective equipment or measures can reduce the risk of damage, so it is also necessary to promote their service and com-ply with labor regulations for agricultural workers.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Javno zdravstvo i zdravstvena zaštita, Farmacija, Biotehnologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA