Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1249022

Semiquantitative classification (SQC) and Oxford classifications predict poor renal outcome better than The International Study of Kidney Disease in Children (ISKDC) and Haas in patients with IgAV nephritis: a multicenter study


Kifer, Nastasia; Bulimbašić, Stela; Šestan, Mario; Held, Martina; Kifer, Domagoj; Sršen, Saša; Gračanin, Ana Gudelj; Heshin-Bekenstein, Merav; Giani, Teresa; Cimaz, Rolando et al.
Semiquantitative classification (SQC) and Oxford classifications predict poor renal outcome better than The International Study of Kidney Disease in Children (ISKDC) and Haas in patients with IgAV nephritis: a multicenter study // Journal of Nephrology (Milano. 1988) (2022) doi:10.1007/s40620-022-01509-4 (znanstveni, online first)


CROSBI ID: 1249022 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Semiquantitative classification (SQC) and Oxford classifications predict poor renal outcome better than The International Study of Kidney Disease in Children (ISKDC) and Haas in patients with IgAV nephritis: a multicenter study

Autori
Kifer, Nastasia ; Bulimbašić, Stela ; Šestan, Mario ; Held, Martina ; Kifer, Domagoj ; Sršen, Saša ; Gračanin, Ana Gudelj ; Heshin-Bekenstein, Merav ; Giani, Teresa ; Cimaz, Rolando ; Gagro, Alenka ; Frković, Marijan ; Ćorić, Marijana ; Jelušić, Marija

Vrsta, podvrsta
Radovi u časopisima, znanstveni

Izvornik
Journal of Nephrology (Milano. 1988) (2022)

Status rada
Online first

Ključne riječi
IgA vasculitis ; Henoch-Schonlein purpura ; Nephritis ; Pathology

Sažetak
Introduction: Several histologic classifications are used in the evaluation of IgA vasculitis nephritis (IgAVN), however, to date, no studies have determined which one has the strongest association with the severity of IgAVN and, as a consequence, its outcomes. Materials and methods: Patients included in the study were diagnosed with IgAV and IgAVN in seven tertiary university medical centers in Croatia, Italy and Israel. The International Study of Kidney Disease in Children (ISKDC), Haas, Oxford, and Semiquantitative classification (SQC) classifications were used in the analysis and description of renal biopsy. Time from biopsy to outcome evaluation was a statistically significant factor in outcome prediction that was used to define the base model, and was a covariate in all the tested models. Results: Sixty-seven patients were included in this study. The SQC classification proved to be the best one in outcome prediction, followed by the Oxford classification. The ISKDC and Haas classifications could not predict renal outcome. The Oxford parameters for mesangial hypercellularity and tubular atrophy, as well as the SQC parameters for cellular crescents showed an independent statistically significant contribution to outcome prediction. High level of twenty-four hour protein excretion was associated with a higher grade in the Oxford, SQC and ISKDC classifications. Endocapillary proliferation was positively associated with the Pediatric Vasculitis Activity Score (PVAS) at diagnosis, while tubular atrophy was negatively associated. Conclusion: The SQC, followed by the Oxford classification were found to provide the best classifications of renal biopsy analysis in patients to predict the outcome in patients with IgAVN. Cellular crescents, mesangial hypercellularity and tubular atrophy showed significant contributions, indicating that active and chronic variables should be included in the estimation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
IP-2019-04-8822 - Histološki, klinički, laboratorijski i genski prediktori ishoda bolesnika s Henoch-Schönleinovom purpurom i nefritisom (PURPURAPREDICTORS) (Jelušić, Marija, HRZZ - 2019-04) ( CroRIS)

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb,
Medicinski fakultet, Split,
Medicinski fakultet, Osijek

Poveznice na cjeloviti tekst rada:

doi link.springer.com

Citiraj ovu publikaciju:

Kifer, Nastasia; Bulimbašić, Stela; Šestan, Mario; Held, Martina; Kifer, Domagoj; Sršen, Saša; Gračanin, Ana Gudelj; Heshin-Bekenstein, Merav; Giani, Teresa; Cimaz, Rolando et al.
Semiquantitative classification (SQC) and Oxford classifications predict poor renal outcome better than The International Study of Kidney Disease in Children (ISKDC) and Haas in patients with IgAV nephritis: a multicenter study // Journal of Nephrology (Milano. 1988) (2022) doi:10.1007/s40620-022-01509-4 (znanstveni, online first)
Kifer, N., Bulimbašić, S., Šestan, M., Held, M., Kifer, D., Sršen, S., Gračanin, A., Heshin-Bekenstein, M., Giani, T. & Cimaz, R. (2022) Semiquantitative classification (SQC) and Oxford classifications predict poor renal outcome better than The International Study of Kidney Disease in Children (ISKDC) and Haas in patients with IgAV nephritis: a multicenter study. Prihvaćen za objavljivanje u Journal of Nephrology (Milano. 1988). [Preprint] doi:10.1007/s40620-022-01509-4.
@unknown{unknown, author = {Kifer, Nastasia and Bulimba\v{s}i\'{c}, Stela and \v{S}estan, Mario and Held, Martina and Kifer, Domagoj and Sr\v{s}en, Sa\v{s}a and Gra\v{c}anin, Ana Gudelj and Heshin-Bekenstein, Merav and Giani, Teresa and Cimaz, Rolando and Gagro, Alenka and Frkovi\'{c}, Marijan and \'{C}ori\'{c}, Marijana and Jelu\v{s}i\'{c}, Marija}, year = {2022}, DOI = {10.1007/s40620-022-01509-4}, keywords = {IgA vasculitis, Henoch-Schonlein purpura, Nephritis, Pathology}, journal = {Journal of Nephrology (Milano. 1988)}, doi = {10.1007/s40620-022-01509-4}, title = {Semiquantitative classification (SQC) and Oxford classifications predict poor renal outcome better than The International Study of Kidney Disease in Children (ISKDC) and Haas in patients with IgAV nephritis: a multicenter study}, keyword = {IgA vasculitis, Henoch-Schonlein purpura, Nephritis, Pathology} }
@unknown{unknown, author = {Kifer, Nastasia and Bulimba\v{s}i\'{c}, Stela and \v{S}estan, Mario and Held, Martina and Kifer, Domagoj and Sr\v{s}en, Sa\v{s}a and Gra\v{c}anin, Ana Gudelj and Heshin-Bekenstein, Merav and Giani, Teresa and Cimaz, Rolando and Gagro, Alenka and Frkovi\'{c}, Marijan and \'{C}ori\'{c}, Marijana and Jelu\v{s}i\'{c}, Marija}, year = {2022}, DOI = {10.1007/s40620-022-01509-4}, keywords = {IgA vasculitis, Henoch-Schonlein purpura, Nephritis, Pathology}, journal = {Journal of Nephrology (Milano. 1988)}, doi = {10.1007/s40620-022-01509-4}, title = {Semiquantitative classification (SQC) and Oxford classifications predict poor renal outcome better than The International Study of Kidney Disease in Children (ISKDC) and Haas in patients with IgAV nephritis: a multicenter study}, keyword = {IgA vasculitis, Henoch-Schonlein purpura, Nephritis, Pathology} }

Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font