Naslov
Case report: A patient with mitochondrial neurogastrointestinal encephalomyopathy and chronic intestinal failure

Autori
Barišić, Ana ; Ljubas Kelečić, Dina ; Vranešić Bender, Darija ; Karas, Irena ; Brinar, Marko ; Miletić, Vladimir ; Krznarić, Željko

Izvornik
Frontiers in Nutrition (2296-861X) 9 (2022); 983873, 6

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
mitochondrial neurogastrointestinal encephalomyopathy ; malnutrition ; home parenteral nutrition ; intestinal failure ; nutrition team

Sažetak
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare disorder commonly diagnosed in later disease stages when it prominently manifests as malnutrition. We report on a female patient diagnosed with MNGIE at the age of 36. She was severely malnourished due to loss of resorptive surface after several surgical procedures, gastrointestinal dysmotility, and small intestinal bacterial overgrowth. Therefore, early and aggressive total parenteral nutrition was introduced. Although no reports have shown that nutritional support can modify the clinical outcome, this case suggests that adequate nutritional support, particularly parenteral nutrition, supervised by an experienced nutritional team, may prolong the lifespan of patients with MNGIE.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA