Naslov
Gender-related differences in the systemic right ventricular failure: a cross-sectional MRI study

Autori
Gregov, Andrija ; Balaško Josipović, Tihana ; Muršić, Miroslav ; Hrabak Paar, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Insights into imaging, 12 (2021), Suppl 2 / - , 2021, A11-A11

Skup
European congress of radiology (ECR 2021)

Mjesto i datum
Online, 03.03.2021. - 07.03.2021

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
systemic right ventricule ; cardiac MRI

Sažetak
Purpose: To detect gender differences in the morphology and function of the systemic right ventricle (SRV) in patients with transposition of the great arteries (TGA). Methods or Background: Cine steady-state free precession cardiac MRI sequences were acquired using a 1, 5T scanner in 25 patients with SRV (age range 19-68, 13 males): 16 with atrial-switch repair for D-TGA and 9 with congenitally-corrected TGA. SRV volumetry was performed using a standard procedure. Mean longitudinal SRV strain was measured on a 4- chamber cine view, and mean circumferential SRV strain at three cine short- axis images based on feature-tracking. Late- gadolinium enhancement (LGE) scanning was performed in 22 patients and visually assessed. Numerical parameters of SRV function were compared between genders using independent samples T-test, whereas differences in LGE were assessed using Chi-Squared test. Results or Findings: Male patients with SRV, compared to their female counterparts, had significantly larger indexed SRV enddiastolic volume (139±47ml/m2 vs. 104±18ml/m2, p=0.025), lower SRV ejection fraction (39±13% vs. 52±5%, p=0.003) and SRV LGE more commonly present (9/12 vs. 1/10, p=0.002). Males had lower mean longitudinal SRV strain (-11.3±2, 8% vs. -16.4±2.4%, p<0.001) and mean circumferential SRV strain in the basal (-11.0±2.9% vs. -15.3±2.6%, p<0.001) and midventricular plane (-10.5±4.1% vs. -14.8±4.0%, p=0.015). There was no significant age difference between males and females. Conclusion: Results of this study suggest that male patients with SRV could have worse parameters of SRV function compared to their female counterparts, but that should be confirmed in a larger group of patients.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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