Naslov
MRI assessment of the systemic right ventricle deformation: a cross-sectional study

Autori
Hrabak Paar, Maja ; Gregov, Andrija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Society of Cardiovascular Radiology (ESCR) Annual Scientific Meeting 2022 ; International Journal of Cardiovascular Imaging 2022, Vol. 38 / - : Springer Science+Business Media, 2022, 2576-2576

Skup
European Society of Cardiovascular Radiology (ESCR) Annual Scientific Meeting 2022

Mjesto i datum
Rim, Italija, 27.10.2022. - 29.10.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cardiac MRI ; strain analysis ; congenital heart disase

Sažetak
Purpose/Objectives: To compare the right ventricle (RV) strain parameters between patients with systemic RV (SRV) and individuals without structural heart disease. Methods & Materials: Cine steady-state free precession cardiac MRI sequences were acquired using a 1, 5 T scanner in short- and long-axis views in 25 patients with SRV (16 with atrial switch repair for D-transposition of great arteries (TGA) and 9 with congenitally corrected TGA ; age range 19–68, 13 males). The control group consisted of 25 individuals without structural heart disease (age range 10–73, 14 males). After performing routine RV MRI volumetry, mean longitudinal RV strain was measured on a 4- chamber view and mean circumferential RV strain from three short-axis images (basal, midventricular, and apical) based on feature tracking using Segment software (Medviso AB, Sweden). The strain parameters between patients with SRV and the control group were compared using an independent samples T-test. Results: Patients with SRV, compared to the control group, had significantly higher RV indexed enddiastolic volume (122 ± 40 ml/m2 vs. 70 ± 9 ml/m2, p\ 0.001), lower RV ejection fraction (EF, 45 ± 12% vs. 62 ± 6%, p <0.001), and reduced mean longitudinal RV strain (-13.7 ± 3.6% vs. -21.6 ± 2.7%, p <0.001). Comparison between patients with systemic right ventricle and individuals from the control group without structural heart disease. There was no relevant difference between mean circumferential SRV strain in the basal and midventricular plane, however in patients with SRV mean circumferential strain was reduced at the apical level (-12.0 ± 6.1% vs. -17.9 ± 5.6%, p \0.001). Mean longitudinal RV strain was reduced in patients with preserved SRV EF (-16.0 ± 2.5%) as compared to the control group (-21.6 ± 2.7%) but was better than in patients with reduced SRV EF (-11.6 ± 3.3%, p <0.001). The mean circumferential RV strain was significantly lower in patients with reduced SRV EF (-9.5 ± 2.3%) compared to those with preserved SRV EF (-15.2 ± 3.6%) and compared to the control group (-15.5 ± 3.2%), but it was not different between patients with preserved SRV EF and controls (p <0.001). Conclusion: In patients with SRV, RV is enlarged and has decreased function compared to control subjects. Unlike mean circumferential RV strain, mean longitudinal RV strain is reduced even in patients with preserved SRV EF, so mean longitudinal RV strain could be an early indicator of SRV impairment and should be measured in patients with SRV.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA