Naslov
Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach
(Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach)

Autori
Duvančić, Tea ; Škokić, Siniša ; Erjavec, Igor ; Plečko, Mihovil ; Bohaček, Ivan ; Gajović, Srećko ; Delimar, Domagoj

Izvornik
Croatian medical journal (0353-9504) 63 (2022), 6; 515-524

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cancellous bone ; humans ; magnetic resonance imaging ; osteoarthritis, hip / diagnostic imaging ; osteoarthritis, hip / surgery ; protons ; x-ray microtomography / methods

Sažetak
Aim: To test the agreement between a newly developed micro-magnetic resonance imaging (MRI) analysis of the subchondral bone and the micro-computed tomography (CT) approach. ----- Methods: Samples obtained from 10 patients with osteoarthritis undergoing total hip arthroplasty were scanned with a 7.0 T micro-MRI. Proton density- weighted images and proton density-weighted images with fat suppression were obtained. The results were validated with a micro-CT device. Micro-MRI and micro-CT scans of the same sample were aligned, and regions of interest were delineated on equal areas of the sample. Bone volume fraction was calculated by using in-house plugins. The agreement between the methods was tested with Bland- Altman analysis. ----- Results: The agreement between the methods was good, with average difference of 2.167%. The differences between the methods were not significant (P=0.272, t test). ----- Conclusion: The novel micro-MRI approach could be used for subchondral bone analysis. With further optimization for clinical MRI machines, the approach can be also used in the diagnostics of hip osteoarthritis.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA