Naslov
Locoregional treatment approaches for hepatocellular carcinoma – a case report

Autori
Sertić Milić, Helga ; Jurjević, Nikolina ; Ferenc, Thomas ; Svetec Dvorski, Jelena ; Zekan Vučetić, Mirta ; Vidjak, Vinko

Izvornik
Libri oncologici : Croatian journal of oncology (0300-8142) 50 (2022), 2-3; 142-145

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
hepatocellular carcinoma ; locoregional therapy ; hepatitis C virus ; liver cirrhosis

Sažetak
A hepatocellular carcinoma (HCC) is a primary liver malignancy, often arising in the setting of chronic liver disease. Incidence of this carcinoma is increasing at a great rate. Disease often manifests asymptomatically and to make the final diagnosis is often challenging. Screening of patients at risk is based on ultrasound (US) examinations, which in the setting of suspicion lesion findings often converts to multiphasic computed tomography (CT) and magnetic resonance imaging (MRI) procedures for advanced disease evaluation. The selection of treatment modality depends on tumor size and location, extrahepatic spread and subsequent liver disease. For years the first line of treatment was liver resection and transplantation. Locoregional therapy is a novel approach to diverse stages of HCC with good response and higher overall survival rates, especially in early stages. Transarterial chemoembolization (TACE) is the method of choice in patients with multifocal HCC and maintained liver function, unsuitable for surgical treatment. We present a patient with HCC in the setting of hepatitis C virus (HCV) infection, treated with combined methods of locoregional therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA