Pretraga

Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1244127

The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg)

(Hp-EuReg Investigators) Caldas, M; Perez-Aisa, A; Tepes, B; Keco-Huerga, A; Bujanda, L; Lucendo, AJ; Rodrigo, L; Vaira, D; Fernandez-Salazar, L; Huguet, JM et al.
The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg) // Antibiotics, 10 (2021), 8; 965, 22 doi:10.3390/antibiotics10080965 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1244127 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg)

Autori
Caldas, M ; Perez-Aisa, A ; Tepes, B ; Keco-Huerga, A ; Bujanda, L ; Lucendo, AJ ; Rodrigo, L ; Vaira, D ; Fernandez-Salazar, L ; Huguet, JM ; Perez-Lasala, J ; Jurecic, NB ; Fadeenko, G ; Barrio, J ; Areia, M ; Ortuno, J ; Pellicano, R ; Leja, M ; Molina-Infante, J ; Bogomolov, P ; Alekseenko, S ; Dominguez-Cajal, M ; Gomez-Camarero, J ; Ntouli, V ; Martinez- Dominguez, SJ ; Ruiz-Zorrilla, R ; Nunez, O ; Sarsenbaeva, AS ; Almela, P ; Phull, P ; Espada, M ; Puig, I ; Nyssen, OP ; Megraud, F ; O'Morain, C ; Gisbert, JP

Kolaboracija
Hp-EuReg Investigators

Izvornik
Antibiotics (2079-6382) 10 (2021), 8; 965, 22

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
statins ; Helicobacter pylori ; treatment

Sažetak
Statins could increase the effectiveness of Helicobacter pylori eradication therapies due to their anti-inflammatory effect. The aim of this study was to analyze the impact of this therapeutic association in real life. This is a multicenter, prospective, non-interventional study aimed at evaluating the management of H. pylori by European gastroenterologists. Patients were registered in an e-CRF by AEG-REDCap from 2013 to 2020. The association between statin use and H. pylori eradication effectiveness was evaluated through multivariate analysis. Overall, 9988 and 705 patients received empirical and culture-guided treatment, respectively. Overall, statin use was associated with higher effectiveness in the empirical group (OR = 1.3 ; 95%CI = 1.1-1.5), but no association was found with first-line treatment effectiveness (N = 7738) ; as an exception, statin use was specifically associated with lower effectiveness of standard triple therapy (OR = 0.76 ; 95%CI = 0.59-0.99). In the rescue therapy empirical group (N = 2228), statins were associated with higher overall effectiveness (OR = 1.9 ; 95%CI = 1.4-2.6). However, sub-analyses by treatment schemes only confirmed this association for the single-capsule bismuth quadruple therapy (OR = 2.8 ; 95%CI = 1.3-5.7). No consistent association was found between statin use and H. pylori therapy effectiveness. Therefore, the addition of statins to the usual H. pylori treatment cannot be currently recommended to improve cure rates.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA

Ustanove:
Medicinski fakultet, Split

Profili:

Avatar Url Božidar Tepeš (autor)

Avatar Url Ante Tonkić (autor)

Poveznice na cjeloviti tekst rada:

doi cris.unibo.it

Citiraj ovu publikaciju:

(Hp-EuReg Investigators) Caldas, M; Perez-Aisa, A; Tepes, B; Keco-Huerga, A; Bujanda, L; Lucendo, AJ; Rodrigo, L; Vaira, D; Fernandez-Salazar, L; Huguet, JM et al.
The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg) // Antibiotics, 10 (2021), 8; 965, 22 doi:10.3390/antibiotics10080965 (međunarodna recenzija, članak, znanstveni)
(Hp-EuReg Investigators) (Hp-EuReg Investigators) Caldas, M., Perez-Aisa, A., Tepes, B., Keco-Huerga, A., Bujanda, L., Lucendo, A., Rodrigo, L., Vaira, D., Fernandez-Salazar, L. & Huguet, J. (2021) The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg). Antibiotics, 10 (8), 965, 22 doi:10.3390/antibiotics10080965.
@article{article, author = {Caldas, M and Perez-Aisa, A and Tepes, B and Keco-Huerga, A and Bujanda, L and Lucendo, AJ and Rodrigo, L and Vaira, D and Fernandez-Salazar, L and Huguet, JM and Perez-Lasala, J and Jurecic, NB and Fadeenko, G and Barrio, J and Areia, M and Ortuno, J and Pellicano, R and Leja, M and Molina-Infante, J and Bogomolov, P and Alekseenko, S and Dominguez-Cajal, M and Gomez-Camarero, J and Ntouli, V and Martinez- Dominguez, SJ and Ruiz-Zorrilla, R and Nunez, O and Sarsenbaeva, AS and Almela, P and Phull, P and Espada, M and Puig, I and Nyssen, OP and Megraud, F and O'Morain, C and Gisbert, JP}, year = {2021}, pages = {22}, DOI = {10.3390/antibiotics10080965}, chapter = {965}, keywords = {statins, Helicobacter pylori, treatment}, journal = {Antibiotics}, doi = {10.3390/antibiotics10080965}, volume = {10}, number = {8}, issn = {2079-6382}, title = {The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg)}, keyword = {statins, Helicobacter pylori, treatment}, chapternumber = {965} }
@article{article, author = {Caldas, M and Perez-Aisa, A and Tepes, B and Keco-Huerga, A and Bujanda, L and Lucendo, AJ and Rodrigo, L and Vaira, D and Fernandez-Salazar, L and Huguet, JM and Perez-Lasala, J and Jurecic, NB and Fadeenko, G and Barrio, J and Areia, M and Ortuno, J and Pellicano, R and Leja, M and Molina-Infante, J and Bogomolov, P and Alekseenko, S and Dominguez-Cajal, M and Gomez-Camarero, J and Ntouli, V and Martinez- Dominguez, SJ and Ruiz-Zorrilla, R and Nunez, O and Sarsenbaeva, AS and Almela, P and Phull, P and Espada, M and Puig, I and Nyssen, OP and Megraud, F and O'Morain, C and Gisbert, JP}, year = {2021}, pages = {22}, DOI = {10.3390/antibiotics10080965}, chapter = {965}, keywords = {statins, Helicobacter pylori, treatment}, journal = {Antibiotics}, doi = {10.3390/antibiotics10080965}, volume = {10}, number = {8}, issn = {2079-6382}, title = {The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp-EuReg)}, keyword = {statins, Helicobacter pylori, treatment}, chapternumber = {965} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

Citati:

    Altmetrijski pokazatelji:


    Podijeli:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font
    CROSBI koristi kolačiće (cookies) kako bi poboljšao funkcionalnost stranice.