Naslov
COMPARISON OF LABORATORY AND CLINICAL PARAMETERS AND PSYCHOLOGICAL FUNCTIONING IN CARDIAC PATIENTS DURING THE COVID-19 PANDEMIC

Autori
Dvornik, Štefica ; Zaninović Jurjević Teodora ; Pokrajac-Bulian, Alessandra ; Đurić, Katja ; Pejić, Domagoj ; Vodopija-Krstanović, Irena ; Ružić, Alen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Clinical Chemistry and Laboratory Medicine 2021 ; 59, Special Suppl, S94 - S835 / Plebani, Mario - Berlin : Walter de Gruyter, 2021, 8-8

Skup
24th IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine (EuroMedlab 2021)

Mjesto i datum
München, Njemačka, 10.04.2022. - 14.04.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
NT-proBNP, glucose, anxiety, depression, HF patients

Sažetak
BACKGROUND-AIM Depression and anxiety in HF (heart failure) patients are a common occurrence and are associated with a poor clinical picture and prognosis, which may worsen significantly during the COVID-19 pandemic, when patients are exposed to more stress. METHODS This study compared hospitalized HF patients’ and cardiovascular outpatients’ psychological, clinical and laboratory parameters. During two months of the pandemic, hospitalized HF patients completed questionnaires to assess their psychological condition. The cardiovascular outpatient control group completed the questionnaires during their cardiological examination. RESULTS The study included 74 hospitalized HF patients (27.03% F and 72.97% M), aged 39 to 89 years (M=70.10 + 11.73) and 74 cardiac outpatients (51.4% F and 48.6% M) aged 27 to 80 years (M=57.35 + 12.61). HF patients were older than outpatients (t(140)=6.49, p<.01). They had significantly lower left ventricular ejection fraction (35.8 vs. 57.15% ; t(97)=9.08, p<.001), higher heart rate (97 vs. 77/min ; t(101)=5.39, p<.001), and systolic pressure (142 vs. 133 mmHg ; t(102)=2.21, p<.05) in comparison with outpatients. They also had significantly lower cholesterol levels (4.0 vs. 5.9 mmol/L ; t(41)=3.57, p<.01) and LDL cholesterol concentrations (2.4 vs. 3.5 mmol/L ; t(43)=2.80, p<.01). HF patients had higher level of depression (r=.38, p<.01), higher fear about heart sensations (r=.28, p<.01), greater avoidance of activities (r=.45, p<.001), and more heart-focused attention (r=.29, p<.01). They reported receiving less support from the environment (r=-.20, p<.05) but more from health professionals (r=.30, p<.01). More depressive HF patients had higher glucose concentration than non-depressive patients. HF patients had elevated NT-proBNP (7297.58 + 8990.11 ng/L) and hs-cTnT (84.52 + 176.46 ng/L) concentrations. There was a significant correlation between anxiety and NT-proBNP concentrations in hospitalized HF patients (r=.33 ; p<.05). CONCLUSIONS NT-proBNP is a well-established biomarker for HF. An association was established between elevated NT-proBNP levels and general anxiety symptoms.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Psihologija

POVEZANOST RADA