Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1239504

Electrochemical Determination of Morphine in Urine Samples by Tailoring FeWO4/CPE Sensor


Ognjanović, Miloš; Nikolić, Katarina; Bošković, Marko; Pastor, Ferenc; Popov, Nina; Marciuš, Marijan; Krehula, Stjepko; Antić, Bratislav; Stanković, Dalibor M.
Electrochemical Determination of Morphine in Urine Samples by Tailoring FeWO4/CPE Sensor // Biosensors, 12 (2022), 932, 13 doi:10.3390/bios12110932 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1239504 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Electrochemical Determination of Morphine in Urine Samples by Tailoring FeWO4/CPE Sensor

Autori
Ognjanović, Miloš ; Nikolić, Katarina ; Bošković, Marko ; Pastor, Ferenc ; Popov, Nina ; Marciuš, Marijan ; Krehula, Stjepko ; Antić, Bratislav ; Stanković, Dalibor M.

Izvornik
Biosensors (2079-6374) 12 (2022); 932, 13

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
iron tungstate ; carbon paste electrode ; electroanalysis ; square wave voltammetry ; morphine ; real-world sample

Sažetak
Morphine (MORPH) is natural alkaloid and mainly used as a pain reliever. Its monitoring in human body fluids is crucial for modern medicine. In this paper, we have developed an electrochemical sensor for submicromolar detection of MORPH. The sensor is based on modified carbon paste electrode (CPE) by investigating the FexW1-xO4 ratio in iron tungstate (FeWO4), as well as the ratio of this material in CPE. For the first time, the effect of the iron–tungsten ratio in terms of achieving the best possible electrochemical characteristics for the detection of an important molecule for humans was examined. Morphological and electrochemical characteristics of materials were studied. The best results were obtained using Fe1W3 and 7.5% of modifier in CPE. For MORPH detection, square wave voltammetry (SWV) was optimized. Under the optimized conditions, Fe1W3@CPE resulted in limit of detection (LOD) of the method of 0.58 µM and limit of quantification (LOQ) of 1.94 µM. The linear operating range between 5 and 85 µM of MORPH in the Britton–Robinson buffer solution (BRBS) at pH 8 as supporting electrolyte was obtained. The Fe1W3@CPE sensor resulted in good selectivity and excellent repeatability with relative standard deviation (RSD) and was applied in real-world samples of human urine. Application for direct MORPH detection, without tedious sample pretreatment procedures, suggests that developed electrochemical sensor has appeared to be a suitable competitor for efficient, precise, and accurate monitoring of the MORPH in biological fluids.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekti:
MZO-RH-RS- - Kompoziti nanočestica miješanih oksida i hidroksida željeza i prijelaznih metala i ugljikovih nanomaterijala za fotokatalitičke i elektrokatalitičke primjene (Krehula, Stjepko, MZO ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Marijan Marciuš (autor)

Avatar Url Stjepko Krehula (autor)

Avatar Url Nina Popov (autor)

Poveznice na cjeloviti tekst rada:

doi doi.org www.mdpi.com fulir.irb.hr

Citiraj ovu publikaciju:

Ognjanović, Miloš; Nikolić, Katarina; Bošković, Marko; Pastor, Ferenc; Popov, Nina; Marciuš, Marijan; Krehula, Stjepko; Antić, Bratislav; Stanković, Dalibor M.
Electrochemical Determination of Morphine in Urine Samples by Tailoring FeWO4/CPE Sensor // Biosensors, 12 (2022), 932, 13 doi:10.3390/bios12110932 (međunarodna recenzija, članak, znanstveni)
Ognjanović, M., Nikolić, K., Bošković, M., Pastor, F., Popov, N., Marciuš, M., Krehula, S., Antić, B. & Stanković, D. (2022) Electrochemical Determination of Morphine in Urine Samples by Tailoring FeWO4/CPE Sensor. Biosensors, 12, 932, 13 doi:10.3390/bios12110932.
@article{article, author = {Ognjanovi\'{c}, Milo\v{s} and Nikoli\'{c}, Katarina and Bo\v{s}kovi\'{c}, Marko and Pastor, Ferenc and Popov, Nina and Marciu\v{s}, Marijan and Krehula, Stjepko and Anti\'{c}, Bratislav and Stankovi\'{c}, Dalibor M.}, year = {2022}, pages = {13}, DOI = {10.3390/bios12110932}, chapter = {932}, keywords = {iron tungstate, carbon paste electrode, electroanalysis, square wave voltammetry, morphine, real-world sample}, journal = {Biosensors}, doi = {10.3390/bios12110932}, volume = {12}, issn = {2079-6374}, title = {Electrochemical Determination of Morphine in Urine Samples by Tailoring FeWO4/CPE Sensor}, keyword = {iron tungstate, carbon paste electrode, electroanalysis, square wave voltammetry, morphine, real-world sample}, chapternumber = {932} }
@article{article, author = {Ognjanovi\'{c}, Milo\v{s} and Nikoli\'{c}, Katarina and Bo\v{s}kovi\'{c}, Marko and Pastor, Ferenc and Popov, Nina and Marciu\v{s}, Marijan and Krehula, Stjepko and Anti\'{c}, Bratislav and Stankovi\'{c}, Dalibor M.}, year = {2022}, pages = {13}, DOI = {10.3390/bios12110932}, chapter = {932}, keywords = {iron tungstate, carbon paste electrode, electroanalysis, square wave voltammetry, morphine, real-world sample}, journal = {Biosensors}, doi = {10.3390/bios12110932}, volume = {12}, issn = {2079-6374}, title = {Electrochemical Determination of Morphine in Urine Samples by Tailoring FeWO4/CPE Sensor}, keyword = {iron tungstate, carbon paste electrode, electroanalysis, square wave voltammetry, morphine, real-world sample}, chapternumber = {932} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font