Naslov
Frequency of micronuclei in peripheral blood of rats exposed to microwave irradiation

Autori
Trosic, Ivancica ; Busljeta, Ivana ; Kasuba, Vilena ; Rozgaj, Ruzica

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
BIOLOGICAL EFFECTS OF EMF-s, PROCEEDINGS RHODES, GREECE, 7-11 October 2002 / KOSTARIKAS, P. - , 2002, 958-962

Skup
BIOLOGICAL EFFECTS OF EMF-s

Mjesto i datum
Rodos, Grčka, 07.10.2002. - 11.10.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
štakori; ozračenost čitavog tijela; 2450 MHz; mikrovalno zračenje; periferna krv; polikromatski eritrociti; mikronukleus
(rats; whole body irradiation; 2450 MHz; microwave irradiation; peripheral blood; polychromatic erythrocyte; micronucleus)

Sažetak
Male Wistar rats were expsed for two hours a day, seven days a week for a month to 2450 MHz radiofrequency microwave (RF/MW) radiation at power density of 5-15 mW/cm2. Sham-exposed rats were used as controls. Experimental animals were euthanized on the final irradiation day of each treated subgroup. Peripheral blood smears were examined for potential genotoxicity by the presence of micronuclei in polychromatic erythrocytes (PCEs). The results for the time-course of PCEs indicated significant differences (p<0.05) for the 2nd, the 8th and the 15th day between sham and treated subgroups. Increased influx of immature erythrocytes into the peripheral circulation at the beginning of the experiment revealed that the proliferation and maturation of erythropoietic cells have been affected by exposure to the 2450 MHz radiation. Such findings are indicators of irradiation effects at the bone marrow erythropoiesis and their consequent reflection in circulating red cells. The incidence of micronuclei/1000 PCEs in peripheral blood was significantly increased (p<0.05) in the subgroup exposed to 8 irradiation treatments of two hours each in comparison to the sham-exposed subgroup. It is likely that an adaptive mechanism, in both erythropoiesis and genotoxicity in rat experimental model, appeared during the subchronic irradiation treatment.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA