Naslov
Determination of naphthoquinones in invasive alien plants Impatiens glandulifera Royle and I. balfourii Hook.f. from Croatia

Autori
Maleš, Željan ; Domijan, Ana-Marija ; Duka, Ivan ; Marić, Tihana ; Bojić, Mirza ; Rimac, Hrvoje ; Mitić, Božena ; Hruševar, Dario ; Barišić, Karmela ; Verbanac, Donatella

Izvornik
Croatica chemica acta (0011-1643) 95 (2022), 5; 1-5

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
invasive alien species, 2-hydroxy-1, 4-naphthoquinone, 2-methoxy-1, 4-naphthoquinone, novel therapeutics, HPLC

Sažetak
The study aimed to develop an HPLC method for a simultaneous determination of 2-hydroxy-1, 4- naphthoquinone (2-HNQ) and 2-methoxy-1, 4- naphthoquinone (2-MNQ) in plant material. The method was implemented to determine naphthoquinones (NQs) in leaves and flowers of the invasive alien species Impatiens glandulifera and I. balfourii collected in Croatia. Two NQs extraction methods from plant material were compared: decoction and ultrasonic extraction. Validation parameters indicate that the developed method is reliable for the simultaneous determination of 2-HNQ and 2-MNQ in plant material. The decoction extraction obtained a higher NQs yield than ultrasonic extraction. In the leaves and flowers of I. glandulifera and I. balfourii only 2-MNQ was detected. Both, I. glandulifera and I. balfourii, had higher 2-MNQ concentrations in flowers than in leaves. A significantly higher 2-MNQ concentration was found in I. glandulifera compared to I. balfourii. Therefore, I. glandulifera can be considered a rich source of 2-MNQ whose antitumor potential is established.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Interdisciplinarne prirodne znanosti, Farmacija

POVEZANOST RADA