Naslov
Systematic review on skin adverse effects of important hazardous hair cosmetic ingredients with a focus on hairdressers.

Autori
Uter, Wolfgang ; Strahwald, Julia ; Hallmann, Sarah ; Johansen, D. Jeanne ; Havmose, S. Martin ; Kezic, Sanja ; van der Molen, F. Henk ; Macan, Jelena ; Babić, Željka ; Franić, Zrinka ; Macan, Marija ; Turk, Rajka ; Symanzik, Cara ; Weinert, Patricia ; John, M. Swen

Izvornik
Contact dermatitis (0105-1873) 86 (2022); 14236, 16

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
CAS no. 106-50-3 ; CAS no. 30618-84-9 ; CAS no. 5421-46-5 ; CAS no. 7727-21-1 ; CAS no. 7727-54-0 ; CAS no. 95-70-5 ; RRID:SCR_001905 ; hairdressers ; occupational diseases ; skin diseases ; systematic review ; workers' health

Sažetak
Background: The burden of occupational hand eczema in hairdressers is high, and (partly strong) allergens abound in the hair cosmetic products they use. Objectives: To systematically review published evidence concerning contact allergy to an indicative list of active ingredients of hair cosmetics, namely, p-phenylenediamine (PPD), toluene-2, 5-diamine (PTD), persulfates, mostly ammonium persulfate (APS), glyceryl thioglycolate (GMTG), and ammonium thioglycolate (ATG), concerning the prevalence of sensitization, particularly in terms of a comparison (relative risk ; RR) between hairdressers and non- hairdressers. Methods: Following a PROSPERO- registered and published protocol, eligible literature published from 2000 to February 2021 was identified, yielding 322 publications, and extracted in standardized publication record forms, also considering risk of bias. Results: Based on 141 publications, the contact allergy prevalence to PPD was 4.3% (95% CI: 3.8-4.9%) in consecutively patch tested patients. Other ingredients were mostly tested in an aimed fashion, yielding variable, and partly high contact allergy prevalence. Where possible, the RR was calculated, yielding an average increased sensitization risk in hairdressers of between 5.4 (PPD) and 3.4 (ATG). Additional evidence related to immediate-type hypersensitivity, experimental results, exposures, and information from case reports was qualitatively synthesized. Conclusions: An excess risk of contact allergy is clearly evident from the pooled published evidence from the last 20 years. This should prompt an improvement in working conditions and product safety.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA