Naslov
CHRONIC TRAUMATIC ENCEPHALOPATHY (CTE) AND SUICIDE
(CHRONIC TRAUMATIC ENCEPHALOPATHY (CTE) AND SUICIDE.)

Autori
Pavlinac, Luka ; Mosković, Danijela ; Peček, Mirta ; Peček Vidaković, Marijana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstract book 2021 Mind & Brain 60th INPC Online / - , 2022, 37-38

Skup
Mind & Brain 60th INPC

Mjesto i datum
Online, 26.-29.5.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
CTE ; suicide

Sažetak
Introduction/Objectives: CTE is a neurodegenerative disorder characterized by forming neurofibrillary tangles, neurites, and inclusions in astrocytes in sulcal depths of the cortex. It was first described in boxers, following repetitive head injury. Now is also recognized in contact sports athletes and military veterans. Symptoms include headaches, anxiety, anger control problems, depression, suicidality, and gambling problems, but also dysarthric speech, ataxia, Parkinsonism, mild cognitive impairment, and dementia. This review aims to investigate the available data on the association between CTE and suicide. Participants, Materials/Methods: Electronic bibliographic databases PubMed and Google Scholar were searched for publications using the following keywords: „chronic traumatic encephalopathy“ and „suicide“. Results: CTE stands for chronic brain degeneration that occurs as an outcome of repeated head traumas, leading to mild traumatic brain injury. Repetitive brain injuries lead to the development of an inflammatory reaction which triggers a reaction mechanism that ultimately results in a shift of the characteristic tau protein out of the cell and leads to its accumulation in brain tissue. Among many symptoms, suicidality has not been considered a feature of CTE for a long time. Only at the beginning of the second decade of this century, did research appear that sought to link the neuropathology of CTE with an increased risk of suicide.The results of a survey conducted among American National Football League (NFL) players led to the conclusion that the incidence of suicidal deaths is significantly more common in recent years than it was in the last century. Particular emphasis is placed on the involvement of life stressors, such as retirement from sport or loss of income, as possible causes of increased suicidality. Given the lack of scientific evidence and numerous multifactorial causes, the results suggest that there is no increased incidence of suicidality among NFL players than among men in the general population. Conclusions: The occurrence of suicidal thoughts in patients with CTE is multifactorial. A minority of former athletes suffer from a mental illness, most commonly depression, which can increase the propensity for suicidal thoughts. Media influence that unprovenly highlights CTE and suicidality connection can also have a psychological effect on athletes. Further study is essential to resolve whether there is a significant correlation between CTE and suicide.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA