Naslov
Photocatalytic transformations of the resveratrol derivative in microflow reactor

Autori
Mlakić, Milena ; Ljubić, Anabela ; Šalić, Anita ; Zelić, Bruno ; Horváth, Ottó ; Milašinović, Valentina ; Gojun, Martin ; Molčanov, Krešimir ; Škorić, Irena

Izvornik
Catalysts (2073-4344) 12 (2022), 12; 1510, 17

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
thienostilbene ; free base porphyrins ; water-soluble manganese porphyrins ; photocatalytic oxygena-tion ; microflow reactor

Sažetak
A simple and efficient protocol is utilized for the transformations studies of a thiophene analogue of E-resveratrol by photocatalytic oxygenation using an anionic and a cationic free- base porphyrin as well as their manganese(III) complexes. The starting substrate was chosen as a representative of heterostilbenes with proven good antioxidant activity. The experiments were carried out in two photoreactor types (batch and microflow reactor) to investigate impact of the reactor type and design on conversion and photoproduct composition. NMR spectroscopy and UHPLC/MS analyses were applied for identification and quantification of four photoproducts (Z-1, 2, 3, and 4), results of isomerization, dimerization, cyclization and oxygenation. Different yields of photoproducts were obtained in a batch reactor and microflow reactor. In the experiments performed in a microflow reactor, Z-1 was most dominant because it was constantly removed from the reaction mixture. Therefore, the formation of other products (2, 3, 4 and undefined) whose precursor is Z-1 was avoided. This was not the case in the experiments performed in a batch reactor. Additionally, all the reactions tested were significantly accelerated in a microflow reactor, making it the preferred reactor type and design for the photocatalytic transformation of resveratrol derivative.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Kemijsko inženjerstvo

POVEZANOST RADA