Naslov
Microbiota research – novel insights into disease etiology

Autori
Čipčić Paljetak, Hana ; Perić, Mihaela ; Matijašić, Mario ; Panek, Marina ; Verbanac, Donatella

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
1st International Congress of Croatian Society of Nutritionists and Dietitians

Mjesto i datum
Zagreb, Hrvatska, 10-11.6.2016

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
crijevna mikrobiota, upalna bolest crijeva
(gut microbiota, inflammatory bowel disease)

Sažetak
Cohabitation with our resident microbiota embarks at the moment of birth and develops through the entire lifespan. Our bodies are home to a large number of distinct microbial communities, with the thickest population in the gastrointestinal tract.The human gut microbiota is estimated to contain over 1000 different bacterial species, as well as commensal fungi and viruses, while the collective microbial genome, the microbiome, contains hundred times more genes than the entire human genome. Recent developments in gene- sequencing technologies and potent bioinformatics tools enabled new insights on how nutrition and microbiota structure affect human physiology, metabolism and immune function, revealing their role in promoting our health and in different disorders. It has been shown that the imbalance of gut homeostasis is associated with many severe pathological conditions including many inflammatory, metabolic, neurological and neoplastic diseases. Therapeutic approaches at the microbiota level, such as dietary interventions with probiotics, prebiotics and symbiotics, represent a promising avenue towards establishing and maintaining of well-being as well as alleviating underlying disease symptoms. Our team is currently investigating host-gut microbiota interactions in newly diagnosed inflammatory bowel disease patients, aiming to correlate nutritional, immunological and endocrine status with the microbiota composition.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA