Naslov
Antimicrobial susceptibility of Staphylococcus pseudintermedius isolated from dogs with pyoderma and otitis externa

Autori
Zečević, Iva ; Perharić, Matko ; Štritof, Zrinka ; Hađina, Suzana ; Benvin, Iva ; Smolec, Ozren ; Habuš, Josipa

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Proceedings of the conference Antimicrobial resistance in veterinary medicine : current state and perspectives / Ružić, Zoran ; Galić, Ivan - Novi Sad : Poljoprivredni fakultet Univerziteta u Novom Sadu, 2022, 88-93

ISBN
978-86-7520-555-5

Skup
Antimicrobial resistance in veterinary medicine - current state and perspectives

Mjesto i datum
Novi Sad, Srbija, 21.07.2022. - 23.07.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
otitis externa, pyoderma, S. pseudintermedius, MRSP, antimicrobial susceptibility

Sažetak
Staphylococcus pseudintermedius is an opportunistic pathogen associated with numerous, localized and systemic, infections in dogs. The external auditory canals and skin are the most common sites of S. pseudintermedius isolation. Antimicrobial resistance in obtained isolates is rising steadily for those antimicrobials that are frequently used. The high prevalence of methicillin-resistant S. pseudintermedius (MRSP) in such infections is of concern and calls for action. The aim of this study was to estimate the frequency of isolation of S. pseudintermedius in canine otitis externa or pyoderma and to determine the antimicrobial susceptibility of the isolates. From January 2021 to May 2022, clinical specimens were collected from 122 dogs with clinical signs of otitis externa and pyoderma. Bacterial growth was detected in 77 (63.1%) dogs. Among the isolated bacteria, a high prevalence of S. pseudintermedius (54.5%) and significant resistance to antimicrobial agents were detected. Only 30.7% of isolates were susceptible to erythromycin and clindamycin, 33.3% to ampicillin, and 42.9% to doxycycline. Higher susceptible rates were observed for amoxycillin/clavulanic acid (69.2%), gentamicin (72.5%), cefalexin (75%), marbofloxacin (76.4%), enrofloxacin (76.6%), and neomycin (76%). A total of 21.4% of the isolated S. pseudintermedius strains were methicillin- resistant (MRSP), with 77.7% of these isolates also described as multidrug-resistant (MDR). According to the increased population of companion animals, these results highlight the importance of MRSP-positive dogs in public health. Implementation of effective AMR control strategies, development of standardized EU antimicrobial treatment guidelines, and national surveillance systems for MRSP in companion animals are urgently needed.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA