Naslov
Resistance in Campylobacter species

Autori
Šoprek, Silvija ; Jurinović, Luka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
13th CROATIAN CONGRESS OF CLINICAL MICROBIOLOGY and 10th CROATIAN CONGRESS ON INFECTIOUS DISEASES with international participation / - Šibenik : Hrvatsko društvo za infektivne bolesti HLZ-a i Hrvatsko društvo za kliničku mikrobiologiju HLZ-a, 2022

Skup
13. hrvatski kongres kliničke mikrobiologije i 10. hrvatski kongres o infektivnim bolestima (CROCMID 2022)

Mjesto i datum
Šibenik, Hrvatska, 20.10.2022. - 23.10.2022

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Recenziran

Ključne riječi
Campylobacter jejuni ; AMR

Sažetak
The most recent reports confirm that campylobacteriosis remains the first most reported zoonoses in humans and the most frequently reported foodborne illness in the European Union. The main cause of enteritis in developing countries and the most commonly diagnosed bacterial pathogen is C. jejuni (90%), while the rest are mostly caused by C.coli and C.lari. It represents a global health challenge due to continuously increasing trends of antimicrobial resistance both in medicine and agriculture and the financial burden of approximately 2.4 billion euros annually estimated for the EU by European Food Safety Authority (EFSA). One of the main factors influencing increasing rates of antimicrobial resistance, especially to fluoroquinolones and macrolides, was the use of these antimicrobial agents in animal production. Susceptibility rates in C.jejuni and C.coli were first reported in Croatia in 2013. Increasing trends and high resistance rates to quinolones are present in both species (approximately 70%). The increasing trend is also present to tetracyclines, but the resistance rates are significantly lower than to quinolones (approximately 40%). Resistance to erythromycin is still low in both species (1%). Data collected and reported over the years are in line with trends reported through different surveillance networks worldwide (European Centre for Disease Prevention and Control-ECDC, Centers for Disease Control and Prevention-CDC, European Food Safety Authority-EFSA). For many years various antibiotic resistance mechanisms and virulence factors have been observed and studied and yet not all have been explained. Mechanisms of Campylobacter resistance to some beta-lactams such as ampicillin and some of the expanded-spectrum cephalosporins are variable and not very clearly defined. It is expected that scientific projects based on the “one health” concept will explain the emergence and spread of the resistance in Campylobacter. One of those projects is EpiCGulls project which already shows interesting results observed in several studies.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita, Veterinarska medicina

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