Naslov
Complex Permittivity of Ex-Vivo Human, Bovine and Porcine Brain Tissues in the Microwave Frequency Range

Autori
Matković, Anđela ; Kordić, Anton ; Jakovčević, Antonia ; Šarolić, Antonio

Izvornik
Diagnostics (2075-4418) 12 (2022), 11; 2580, 24

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
dielectric properties measurement ; complex permittivity ; microwave gigahertz (GHz) frequency range ; open-ended coaxial probe ; biological tissues ; white matter ; grey matter ; cerebellum ; human, bovine and porcine brain

Sažetak
Accurate knowledge about the dielectric properties of biological tissues in the microwave frequency range may lead to advancement of biomedical applications based on microwave technology. However, the published data are very scarce, especially for human brain tissues. The aim of this work was to measure and report the complex permittivity of brain white matter, grey matter and cerebellum. Complex permittivity was measured on human, bovine and porcine brain tissues in the microwave frequency range from 0.5 to 18 GHz using an open-ended coaxial probe. The results present a valuable addition to the available data on the brain tissue complex permittivity. Some noticeable variations between the results lead to several conclusions. Complex permittivity variation within the same tissue type of the individual species was comparable to interspecies variation. The difference was prominent between human brains obtained from autopsies, while bovine brains obtained from healthy animals showed very similar complex permittivity. We hypothesize that the difference might have been caused by the basic pathologies of the patients, where the associated therapies could have affected the brain water content. We also examined the effect of excised tissue degradation on its complex permittivity over the course of three days, and the results suggest the gradual dehydration of the samples.

Izvorni jezik
Engleski

Znanstvena područja
Elektrotehnika, Temeljne medicinske znanosti, Kliničke medicinske znanosti

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