Naslov
Ion influence on pretransition of multilamellar phosphatidylcholine liposomes

Autori
Bakarić, Danijela ; Domazet, Jurašin, Darija ; Brkljača, Zlatko ; Maleš, Petra

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
27th Croatian Meeting of Chemists and Chemical Engineers and 5th Symposium Vladimir Prelog : Book of Abstracts / Marković, Dean ; Meštrović, Ernest ; Namjesnik, Danijel ; Tomašić, Vesna - Zagreb : Hrvatsko kemijsko društvo, 2021, 151-151

Skup
27. HSKIKI : 27th Croatian Meeting of Chemists and Chemical Engineers and 5th Symposium Vladimir Prelog : Book of Abstracts

Mjesto i datum
Veli Lošinj, Hrvatska, 05.10.2021. - 08.10.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Phosphatidylcholine ; Liposomes ; Ions

Sažetak
Depending on temperature and composition, lipid bilayers can exist in different phases among which the most significant are those of gel (Lβ’) and fluid (Lα) phase, respectively. The transition between these phases (Lβ’ → Lα) is assigned as the main phase transition and has a peak at melting temperature (Tm). One of the most puzzling phases in lipid bilayers constituted from 1, 2- dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) is ripple phase (Pβ’) which is characterized by periodically undulations of lipid bilayer, and usually appears few degrees below Tm (Tp ; Tp<Tm). A promising strategy in characterization of lipid phase transitions includes differential scanning calorimetry and spectroscopic techniques, the results of which are supported with appropriate chemometric tool. As small changes in aqueous environment can exert significant impact on the arrangement of lipid bilayers of DPPC, the effect of qualitatively different buffers of different pH values on ripple phase of DPPC was examined. All experimental results are supplemented with computational study.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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