Naslov
Difference in treatment of pituitary incidentalomas in two patients with no endocrinopathies

Autori
Miočić, Zara ; Arambašić, Lea ; Galić, Petra ; Bodakoš, Karla ; Petrović, Ana ; Bilić-Ćurčić, Ines

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
4th International Translational Medicine Congress of Students and Young Physicians OSCON : book of abstracts / Pavlović, Vedrana - Osijek, 2022, 97-97

Skup
4th International Translational Medicine Congress of Students and Young Physicians (OSCON 2022)

Mjesto i datum
Osijek, Hrvatska, 31.03.2022. - 02.04.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
endocrinology ; hypersecretion ; hypopituitarism ; MRI ; pituitary diseases

Sažetak
Pituitary incidentalomas represent previously unsuspected pituitary lesions, divided into microincidentalomas and macroincidentlomas. They are commonly found by CT or MRI scans indicated for unrealted, non-pituitary disease. Although pathohistological mechanisms and etiology is unclear, 90% of pituitary incidentalomas include benign adenomas. Case report: We present two patients with different diagnosis and treatment of pituitary incidentaloma. First patient is a 25 year-old woman with non-specific headaches, but without clinical signs of endocrinopathy. She has regular menstrual cycles without galactorrhea. Magnetic resonance imaging (MRI) showed microadenoma 5-6 millimeters in size. Initial tests included analysis for hormone hypersecretion and hypopituitarism. Laboratory results revealed increased prolactin. According to the findings, the diagnosis was non secretory microadenoma. No therapy was prescribed, only regular check-ups. Second patient is a 70-year-old woman with frequent headaches, but also without clinical signs of endocrinopathy. MRI showed deformed sella turcica due to an expansive formation extending craniocaudal, more likely corresponding to macroadenoma. Laboratory exams discovered decreased luteinizing hormone (LH) and follicle stimulating hormone (FSH), while prolactin (PRL), thyroid stimulating hormone (TSH) and free thyroxine (fT4) were increased. Examination by ophthalmologist revealed severe pale left optic nerve and bitemporal hemianopia. Surgery was recommended. Conclusion: To conclude, decision about appropriate course of treatment and follow up is based on the results of MRI, computed tomography (CT), visual field examination and basal dynamic hormonal or assessments. Not all incidentalomas require neurosurgical intervention. If not treated surgically, patients are treated conservatively, with regular check-ups, imaging studies and hormonal assessments.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

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