Naslov
Morphological characteristics of Leydig cells in patients with non-obstructive azoospermia

Autori
Hauptman, Dinko ; Marić, Tihana ; Himelreich Perić, Marta ; Zimak, Zoran ; Katušić Bojanac, Ana ; Kaštelan, Željko ; Ježek, Davor

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
4th Andrology Symposium

Mjesto i datum
Zagreb, Hrvatska, 01.07.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
azoospermia ; Leydig cells ; hyperplasia ; stereology

Sažetak
Non-obstructive azoospermia (NOA) is a form of male infertility caused by disorders of the testicular parenchyma and impaired spermatogenesis. This study aimed to investigate the nature of Leydig cell changes in patients with NOA, especially wether their actual proliferation ocurred. Qualitative histological analysis of the control group of patients (men with obstructive azoospermia and fully preserved morphology of the testicular parenchyma) and biopsies of patients with NOA showed a significant difference in the degree of preservation of spermatogenesis and morphology of Leydig cells. The group of infertile men with NOA Leydig cells sometimes displayed an abundant cytoplasm and were organized into large clusters.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA