Naslov
Topical medication as an initial therapeutic option for protruding and non-protruding condylomata acuminata of the distal urethra
(Topical medication as an initial therapeutic option for protruding and non-protruding condylomata acuminata of the distal urethra)

Autori
Meštrović, Tomislav ; Sviben, Mario ; Zember, Sanja ; Drenjančević, Domagoj

Izvornik
BMJ case reports (1757-790X) 14 (2021), 9; E243618, 4

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
dermatology ; human papilloma virus (HPV) ; sexual health ; urology ; microbiology

Sažetak
Genital warts (also known as condylomata acuminata) caused by the human papillomavirus (HPV) represent one of the most common sexually transmitted infections. Although they are usually found in the outer genital region, a small proportion of men can present with (often unrecognised) intraurethral warts, generally limited to the distal urethra and urethral meatus. This poses a treatment challenge not adequately addressed by the current guidelines. Here, we present two cases of low-risk HPV-positive patients with protruding and non-protruding condylomata acuminata of the distal urethra, which were treated successfully by using two different topical regimens (ie, a combination of policresulen and imiquimod for one patient and 5- fluorouracil monotherapy for the other). Although this type of management results in lower rates of tissue destruction and complications and may be given preference as an initial therapeutic option, additional prospective comparative clinical studies are needed to elucidate its potential in similar cases.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA