Pregled bibliografske jedinice broj: 1218587
Blood brain barrier permeability of selenium nanoparticles
Blood brain barrier permeability of selenium nanoparticles // Programme and Abstract booklet
Limassol, Cipar, 2022. str. 185-185 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1218587 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Blood brain barrier permeability of selenium
nanoparticles
Autori
Peranić, Nikolina ; Kalčec, Nikolina ; Ilić, Krunoslav ; Vinković Vrček, Ivana
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Programme and Abstract booklet
/ - , 2022, 185-185
Skup
Nanoweek 2021
Mjesto i datum
Limassol, Cipar, 20.06.2022. - 24.06.2022
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
selenium nanoparticles ; blood-brain barrier ; L-dopa
Sažetak
The blood-brain barrier (BBB) protects the brain from toxic substances but also blocks the entry of many drugs into brain. Thus, brain specific drug delivery is one of the most challenging areas of research, such as therapy for Parkinson's disease. This research aimed to develop more efficient drug delivery system for Parkinson's disease based on selenium nanoparticles (SeNPs). SeNPs display lot of features that make them suitable for drug delivery system as simple preparation, antioxidant activity and neuroprotective effects. We prepared SeNPs functionalized with polyvinylpyrrolidone (PVP) and polysorbate 20 (Tween 20) and tested their delivery efficacy using L-3, 4- diydroxyphenylalanine (L-dopa) as model drug.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb
Profili:
Nikolina Kalčec
(autor)
Ivana Vinković Vrček
(autor)
Krunoslav Ilić
(autor)
Nikolina Peranić
(autor)
